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441 results

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Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma.
Bryant J, Batis N, Franke AC, Clancey G, Hartley M, Ryan G, Brooks J, Southam AD, Barnes N, Parish J, Roberts S, Khanim F, Spruce R, Mehanna H. Bryant J, et al. Among authors: hartley m. Oncotarget. 2019 Aug 27;10(50):5229-5244. doi: 10.18632/oncotarget.27156. eCollection 2019 Aug 27. Oncotarget. 2019. PMID: 31497252 Free PMC article.
Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle.
Wasson CW, Morgan EL, Müller M, Ross RL, Hartley M, Roberts S, Macdonald A. Wasson CW, et al. Among authors: hartley m. Oncotarget. 2017 Oct 6;8(61):103581-103600. doi: 10.18632/oncotarget.21658. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262586 Free PMC article.
Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer.
Brooks JM, Menezes AN, Ibrahim M, Archer L, Lal N, Bagnall CJ, von Zeidler SV, Valentine HR, Spruce RJ, Batis N, Bryant JL, Hartley M, Kaul B, Ryan GB, Bao R, Khattri A, Lee SP, Ogbureke KUE, Middleton G, Tennant DA, Beggs AD, Deeks J, West CML, Cazier JB, Willcox BE, Seiwert TY, Mehanna H. Brooks JM, et al. Among authors: hartley m. Clin Cancer Res. 2019 Sep 1;25(17):5315-5328. doi: 10.1158/1078-0432.CCR-18-3314. Epub 2019 Jun 10. Clin Cancer Res. 2019. PMID: 31182433
Human papillomavirus type 1 E1^E4 protein is a potent inhibitor of the serine-arginine (SR) protein kinase SRPK1 and inhibits phosphorylation of host SR proteins and of the viral transcription and replication regulator E2.
Prescott EL, Brimacombe CL, Hartley M, Bell I, Graham S, Roberts S. Prescott EL, et al. Among authors: hartley m. J Virol. 2014 Nov;88(21):12599-611. doi: 10.1128/JVI.02029-14. Epub 2014 Aug 20. J Virol. 2014. PMID: 25142587 Free PMC article.
Galleria mellonella as an alternative model of Coxiella burnetii infection.
Norville IH, Hartley MG, Martinez E, Cantet F, Bonazzi M, Atkins TP. Norville IH, et al. Among authors: hartley mg. Microbiology (Reading). 2014 Jun;160(Pt 6):1175-1181. doi: 10.1099/mic.0.077230-0. Epub 2014 Mar 27. Microbiology (Reading). 2014. PMID: 24677067 Free article.
Evaluation of the Efficacy of Doxycycline, Ciprofloxacin, Levofloxacin, and Co-trimoxazole Using In Vitro and In Vivo Models of Q Fever.
Clay KA, Hartley MG, Armstrong S, Bewley KR, Godwin K, Rayner E, Vipond J, Bailey M, Atkins TP, Norville IH. Clay KA, et al. Among authors: hartley mg. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0067321. doi: 10.1128/AAC.00673-21. Epub 2021 Aug 9. Antimicrob Agents Chemother. 2021. PMID: 34370577 Free PMC article.
441 results