Qi J - Search Results

1

Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions.

Kong W, Hayashi T, Fiches G, Xu Q, Li MZ, Que J, Liu S, Zhang W, Qi J, Santoso N, Elledge SJ, Zhu J. Kong W, et al. Among authors: qi j. Genomics Proteomics Bioinformatics. 2019 Jun;17(3):319-331. doi: 10.1016/j.gpb.2018.12.010. Epub 2019 Sep 5. Genomics Proteomics Bioinformatics. 2019. PMID: 31494268 Free PMC article.

2

Biased multicomponent reactions to develop novel bromodomain inhibitors.

McKeown MR, Shaw DL, Fu H, Liu S, Xu X, Marineau JJ, Huang Y, Zhang X, Buckley DL, Kadam A, Zhang Z, Blacklow SC, Qi J, Zhang W, Bradner JE. McKeown MR, et al. Among authors: qi j. J Med Chem. 2014 Nov 13;57(21):9019-27. doi: 10.1021/jm501120z. Epub 2014 Oct 31. J Med Chem. 2014. PMID: 25314271 Free PMC article.

3

Inhibition of Polo-like kinase 1 (PLK1) facilitates the elimination of HIV-1 viral reservoirs in CD4⁺ T cells ex vivo.

Zhou D, Hayashi T, Jean M, Kong W, Fiches G, Biswas A, Liu S, Yosief HO, Zhang X, Bradner J, Qi J, Zhang W, Santoso N, Zhu J. Zhou D, et al. Among authors: qi j. Sci Adv. 2020 Jul 15;6(29):eaba1941. doi: 10.1126/sciadv.aba1941. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832623 Free PMC article.

4

Development of Dimethylisoxazole-Attached Imidazo[1,2-a]pyridines as Potent and Selective CBP/P300 Inhibitors.

Muthengi A, Wimalasena VK, Yosief HO, Bikowitz MJ, Sigua LH, Wang T, Li D, Gaieb Z, Dhawan G, Liu S, Erickson J, Amaro RE, Schönbrunn E, Qi J, Zhang W. Muthengi A, et al. Among authors: qi j. J Med Chem. 2021 May 13;64(9):5787-5801. doi: 10.1021/acs.jmedchem.0c02232. Epub 2021 Apr 19. J Med Chem. 2021. PMID: 33872011 Free PMC article.

5

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.

Dai X, Gan W, Li X, Wang S, Zhang W, Huang L, Liu S, Zhong Q, Guo J, Zhang J, Chen T, Shimizu K, Beca F, Blattner M, Vasudevan D, Buckley DL, Qi J, Buser L, Liu P, Inuzuka H, Beck AH, Wang L, Wild PJ, Garraway LA, Rubin MA, Barbieri CE, Wong KK, Muthuswamy SK, Huang J, Chen Y, Bradner JE, Wei W. Dai X, et al. Among authors: qi j. Nat Med. 2017 Sep;23(9):1063-1071. doi: 10.1038/nm.4378. Epub 2017 Aug 14. Nat Med. 2017. PMID: 28805820 Free PMC article.

6

Structure-Guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors.

Liu S, Yosief HO, Dai L, Huang H, Dhawan G, Zhang X, Muthengi AM, Roberts J, Buckley DL, Perry JA, Wu L, Bradner JE, Qi J, Zhang W. Liu S, et al. Among authors: qi j. J Med Chem. 2018 Sep 13;61(17):7785-7795. doi: 10.1021/acs.jmedchem.8b00765. Epub 2018 Aug 30. J Med Chem. 2018. PMID: 30125504 Free PMC article.

7

Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma.

Zhao X, Wang MY, Jiang H, Lwin T, Park PM, Gao J, Meads MB, Ren Y, Li T, Sun J, Fahmi NA, Singh S, Sehgal L, Wang X, Silva AS, Sotomayor EM, Shain KH, Cleveland JL, Wang M, Zhang W, Qi J, Shah BD, Tao J. Zhao X, et al. Among authors: qi j. Cell Rep. 2021 Mar 16;34(11):108870. doi: 10.1016/j.celrep.2021.108870. Cell Rep. 2021. PMID: 33730585 Free PMC article.

8

Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6.

Hu YJ, Belaghzal H, Hsiao WY, Qi J, Bradner JE, Guertin DA, Sif S, Imbalzano AN. Hu YJ, et al. Among authors: qi j. Nucleic Acids Res. 2015 Sep 18;43(16):7790-804. doi: 10.1093/nar/gkv645. Epub 2015 Jun 27. Nucleic Acids Res. 2015. PMID: 26117538 Free PMC article.

9

Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA.

Zou Z, Huang B, Wu X, Zhang H, Qi J, Bradner J, Nair S, Chen LF. Zou Z, et al. Among authors: qi j. Oncogene. 2014 May 1;33(18):2395-404. doi: 10.1038/onc.2013.179. Epub 2013 May 20. Oncogene. 2014. PMID: 23686307 Free PMC article.

10

Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling.

Wu X, Qi J, Bradner JE, Xiao G, Chen LF. Wu X, et al. Among authors: qi j. J Biol Chem. 2013 Dec 13;288(50):36094-105. doi: 10.1074/jbc.M113.485029. Epub 2013 Nov 4. J Biol Chem. 2013. PMID: 24189064 Free PMC article.

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