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Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction.
Vasistha NA, Johnstone M, Barton SK, Mayerl SE, Thangaraj Selvaraj B, Thomson PA, Dando O, Grünewald E, Alloza C, Bastin ME, Livesey MR, Economides K, Magnani D, Makedonopolou P, Burr K, Story DJ, Blackwood DHR, Wyllie DJA, McIntosh AM, Millar JK, Ffrench-Constant C, Hardingham GE, Lawrie SM, Chandran S. Vasistha NA, et al. Among authors: johnstone m. Mol Psychiatry. 2019 Nov;24(11):1641-1654. doi: 10.1038/s41380-019-0505-2. Epub 2019 Sep 3. Mol Psychiatry. 2019. PMID: 31481758 Free PMC article.
DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness.
Malavasi ELV, Economides KD, Grünewald E, Makedonopoulou P, Gautier P, Mackie S, Murphy LC, Murdoch H, Crummie D, Ogawa F, McCartney DL, O'Sullivan ST, Burr K, Torrance HS, Phillips J, Bonneau M, Anderson SM, Perry P, Pearson M, Constantinides C, Davidson-Smith H, Kabiri M, Duff B, Johnstone M, Polites HG, Lawrie SM, Blackwood DH, Semple CA, Evans KL, Didier M, Chandran S, McIntosh AM, Price DJ, Houslay MD, Porteous DJ, Millar JK. Malavasi ELV, et al. Among authors: johnstone m. Transl Psychiatry. 2018 Sep 6;8(1):184. doi: 10.1038/s41398-018-0228-1. Transl Psychiatry. 2018. PMID: 30190480 Free PMC article.
Reversal of proliferation deficits caused by chromosome 16p13.11 microduplication through targeting NFκB signaling: an integrated study of patient-derived neuronal precursor cells, cerebral organoids and in vivo brain imaging.
Johnstone M, Vasistha NA, Barbu MC, Dando O, Burr K, Christopher E, Glen S, Robert C, Fetit R, Macleod KG, Livesey MR, Clair DS, Blackwood DHR, Millar K, Carragher NO, Hardingham GE, Wyllie DJA, Johnstone EC, Whalley HC, McIntosh AM, Lawrie SM, Chandran S. Johnstone M, et al. Among authors: johnstone ec. Mol Psychiatry. 2019 Feb;24(2):294-311. doi: 10.1038/s41380-018-0292-1. Epub 2018 Nov 6. Mol Psychiatry. 2019. PMID: 30401811 Free PMC article.
Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank.
Barbu MC, Zeng Y, Shen X, Cox SR, Clarke TK, Gibson J, Adams MJ, Johnstone M, Haley CS, Lawrie SM, Deary IJ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team; McIntosh AM, Whalley HC. Barbu MC, et al. Among authors: johnstone m. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Jan;4(1):91-100. doi: 10.1016/j.bpsc.2018.07.006. Epub 2018 Jul 31. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019. PMID: 30197049 Free PMC article.
Effects of a mis-sense DISC1 variant on brain activation in two cohorts at high risk of bipolar disorder or schizophrenia.
Whalley HC, Sussmann JE, Johnstone M, Romaniuk L, Redpath H, Chakirova G, Mukherjee P, Hall J, Johnstone EC, Lawrie SM, McIntosh AM. Whalley HC, et al. Among authors: johnstone m, johnstone ec. Am J Med Genet B Neuropsychiatr Genet. 2012 Apr;159B(3):343-53. doi: 10.1002/ajmg.b.32035. Epub 2012 Feb 15. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22337479
Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness.
Johnstone M, Maclean A, Heyrman L, Lenaerts AS, Nordin A, Nilsson LG, De Rijk P, Goossens D, Adolfsson R, St Clair DM, Hall J, Lawrie SM, McIntosh AM, Del-Favero J, Blackwood DH, Pickard BS. Johnstone M, et al. Mol Neuropsychiatry. 2015 Oct;1(3):175-190. doi: 10.1159/000438788. Epub 2015 Oct 7. Mol Neuropsychiatry. 2015. PMID: 27239468 Free PMC article.
Synaptic scaffold evolution generated components of vertebrate cognitive complexity.
Nithianantharajah J, Komiyama NH, McKechanie A, Johnstone M, Blackwood DH, St Clair D, Emes RD, van de Lagemaat LN, Saksida LM, Bussey TJ, Grant SG. Nithianantharajah J, et al. Among authors: johnstone m. Nat Neurosci. 2013 Jan;16(1):16-24. doi: 10.1038/nn.3276. Epub 2012 Dec 2. Nat Neurosci. 2013. PMID: 23201973 Free PMC article.
539 results