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An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.
Futch HS, McFarland KN, Moore BD, Kuhn MZ, Giasson BI, Ladd TB, Scott KA, Shapiro MR, Nosacka RL, Goodwin MS, Ran Y, Cruz PE, Ryu DH, Croft CL, Levites Y, Janus C, Chakrabarty P, Judge AR, Brusko TM, de Kloet AD, Krause EG, Golde TE. Futch HS, et al. Among authors: janus c. J Exp Med. 2019 Nov 4;216(11):2479-2491. doi: 10.1084/jem.20190430. Epub 2019 Aug 29. J Exp Med. 2019. PMID: 31467037 Free PMC article.
Short Aβ peptides attenuate Aβ42 toxicity in vivo.
Moore BD, Martin J, de Mena L, Sanchez J, Cruz PE, Ceballos-Diaz C, Ladd TB, Ran Y, Levites Y, Kukar TL, Kurian JJ, McKenna R, Koo EH, Borchelt DR, Janus C, Rincon-Limas D, Fernandez-Funez P, Golde TE. Moore BD, et al. Among authors: janus c. J Exp Med. 2018 Jan 2;215(1):283-301. doi: 10.1084/jem.20170600. Epub 2017 Dec 5. J Exp Med. 2018. PMID: 29208777 Free PMC article.
TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.
Chakrabarty P, Li A, Ladd TB, Strickland MR, Koller EJ, Burgess JD, Funk CC, Cruz PE, Allen M, Yaroshenko M, Wang X, Younkin C, Reddy J, Lohrer B, Mehrke L, Moore BD, Liu X, Ceballos-Diaz C, Rosario AM, Medway C, Janus C, Li HD, Dickson DW, Giasson BI, Price ND, Younkin SG, Ertekin-Taner N, Golde TE. Chakrabarty P, et al. Among authors: janus c. J Exp Med. 2018 Sep 3;215(9):2247-2264. doi: 10.1084/jem.20180484. J Exp Med. 2018. PMID: 30158114 Free PMC article.
Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.
Ayers JI, Fromholt S, Sinyavskaya O, Siemienski Z, Rosario AM, Li A, Crosby KW, Cruz PE, DiNunno NM, Janus C, Ceballos-Diaz C, Borchelt DR, Golde TE, Chakrabarty P, Levites Y. Ayers JI, et al. Among authors: janus c. Mol Ther. 2015 Jan;23(1):53-62. doi: 10.1038/mt.2014.180. Epub 2014 Sep 17. Mol Ther. 2015. PMID: 25228069 Free PMC article.
Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts.
Moore BD, Levites Y, Xu G, Hampton H, Adamo MF, Croft CL, Futch HS, Moran C, Fromholt S, Janus C, Prokop S, Dickson D, Lewis J, Giasson BI, Golde TE, Borchelt DR. Moore BD, et al. Among authors: janus c. Free Neuropathol. 2022 Jan 11;3(9):3-9. doi: 10.17879/freeneuropathology-2022-3766. Epub 2022 Mar 23. Free Neuropathol. 2022. PMID: 35494163 Free PMC article.
Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy.
Koller EJ, Gonzalez De La Cruz E, Machula T, Ibanez KR, Lin WL, Williams T, Riffe CJ, Ryu D, Strang KH, Liu X, Janus C, Golde TE, Dickson D, Giasson BI, Chakrabarty P. Koller EJ, et al. Among authors: janus c. Hum Mol Genet. 2019 Oct 1;28(19):3255-3269. doi: 10.1093/hmg/ddz151. Hum Mol Genet. 2019. PMID: 31261380 Free PMC article.
Homing in on intracellular Abeta?
Golde TE, Janus C. Golde TE, et al. Among authors: janus c. Neuron. 2005 Mar 3;45(5):639-42. doi: 10.1016/j.neuron.2005.02.013. Neuron. 2005. PMID: 15748837 Free article. Review.
214 results