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Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling.
Feelisch M, Akaike T, Griffiths K, Ida T, Prysyazhna O, Goodwin JJ, Gollop ND, Fernandez BO, Minnion M, Cortese-Krott MM, Borgognone A, Hayes RM, Eaton P, Frenneaux MP, Madhani M. Feelisch M, et al. Among authors: prysyazhna o. Cardiovasc Res. 2020 Jan 1;116(1):51-62. doi: 10.1093/cvr/cvz202. Cardiovasc Res. 2020. PMID: 31372656 Free PMC article.
Protein kinase G oxidation is a major cause of injury during sepsis.
Rudyk O, Phinikaridou A, Prysyazhna O, Burgoyne JR, Botnar RM, Eaton P. Rudyk O, et al. Among authors: prysyazhna o. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9909-13. doi: 10.1073/pnas.1301026110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716652 Free PMC article.
Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice.
Burgoyne JR, Rudyk O, Cho HJ, Prysyazhna O, Hathaway N, Weeks A, Evans R, Ng T, Schröder K, Brandes RP, Shah AM, Eaton P. Burgoyne JR, et al. Among authors: prysyazhna o. Nat Commun. 2015 Aug 10;6:7920. doi: 10.1038/ncomms8920. Nat Commun. 2015. PMID: 26258640 Free article.
Analysis of Mitochondrial Proteins in the Surviving Myocardium after Ischemia Identifies Mitochondrial Pyruvate Carrier Expression as Possible Mediator of Tissue Viability.
Fernández-Caggiano M, Prysyazhna O, Barallobre-Barreiro J, CalviñoSantos R, Aldama López G, Generosa Crespo-Leiro M, Eaton P, Doménech N. Fernández-Caggiano M, et al. Among authors: prysyazhna o. Mol Cell Proteomics. 2016 Jan;15(1):246-55. doi: 10.1074/mcp.M115.051862. Epub 2015 Nov 18. Mol Cell Proteomics. 2016. PMID: 26582072 Free PMC article.
33 results