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Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling.
Feelisch M, Akaike T, Griffiths K, Ida T, Prysyazhna O, Goodwin JJ, Gollop ND, Fernandez BO, Minnion M, Cortese-Krott MM, Borgognone A, Hayes RM, Eaton P, Frenneaux MP, Madhani M. Feelisch M, et al. Among authors: madhani m. Cardiovasc Res. 2020 Jan 1;116(1):51-62. doi: 10.1093/cvr/cvz202. Cardiovasc Res. 2020. PMID: 31372656 Free PMC article.
Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor.
Villar IC, Panayiotou CM, Sheraz A, Madhani M, Scotland RS, Nobles M, Kemp-Harper B, Ahluwalia A, Hobbs AJ. Villar IC, et al. Among authors: madhani m. Cardiovasc Res. 2007 Jun 1;74(3):515-25. doi: 10.1016/j.cardiores.2007.02.032. Epub 2007 Mar 3. Cardiovasc Res. 2007. PMID: 17391657 Free PMC article.
Cysteine redox sensor in PKGIa enables oxidant-induced activation.
Burgoyne JR, Madhani M, Cuello F, Charles RL, Brennan JP, Schröder E, Browning DD, Eaton P. Burgoyne JR, et al. Among authors: madhani m. Science. 2007 Sep 7;317(5843):1393-7. doi: 10.1126/science.1144318. Epub 2007 Aug 23. Science. 2007. PMID: 17717153
Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite.
Maher AR, Arif S, Madhani M, Abozguia K, Ahmed I, Fernandez BO, Feelisch M, O'Sullivan AG, Christopoulos A, Sverdlov AL, Ngo D, Dautov R, James PE, Horowitz JD, Frenneaux MP. Maher AR, et al. Among authors: madhani m. Br J Pharmacol. 2013 Jun;169(3):659-70. doi: 10.1111/bph.12152. Br J Pharmacol. 2013. PMID: 23472879 Free PMC article. Clinical Trial.
Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI).
Siddiqi N, Bruce M, Neil CJ, Jagpal B, Maclennon G, Cotton SC, Papadopoulo SA, Bunce N, Lim P, Schwarz K, Singh S, Hildick-Smith D, Horowitz JD, Madhani M, Boon N, Kaski JC, Dawson D, Frenneaux MP. Siddiqi N, et al. Among authors: madhani m. J Transl Med. 2013 May 6;11:116. doi: 10.1186/1479-5876-11-116. J Transl Med. 2013. PMID: 23648219 Free PMC article. Clinical Trial.
Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans.
Arif S, Borgognone A, Lin EL, O'Sullivan AG, Sharma V, Drury NE, Menon A, Nightingale P, Mascaro J, Bonser RS, Horowitz JD, Feelisch M, Frenneaux MP, Madhani M. Arif S, et al. Among authors: madhani m. Br J Pharmacol. 2015 Jul;172(13):3341-52. doi: 10.1111/bph.13122. Epub 2015 Apr 29. Br J Pharmacol. 2015. PMID: 25754766 Free PMC article.
43 results