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Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness.
Sharma A, Oonthonpan L, Sheldon RD, Rauckhorst AJ, Zhu Z, Tompkins SC, Cho K, Grzesik WJ, Gray LR, Scerbo DA, Pewa AD, Cushing EM, Dyle MC, Cox JE, Adams C, Davies BS, Shields RK, Norris AW, Patti G, Zingman LV, Taylor EB. Sharma A, et al. Among authors: dyle mc. Elife. 2019 Jul 18;8:e45873. doi: 10.7554/eLife.45873. Elife. 2019. PMID: 31305240 Free PMC article.
Role of ATF4 in skeletal muscle atrophy.
Adams CM, Ebert SM, Dyle MC. Adams CM, et al. Among authors: dyle mc. Curr Opin Clin Nutr Metab Care. 2017 May;20(3):164-168. doi: 10.1097/MCO.0000000000000362. Curr Opin Clin Nutr Metab Care. 2017. PMID: 28376050 Review.
Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.
Ebert SM, Dyle MC, Bullard SA, Dierdorff JM, Murry DJ, Fox DK, Bongers KS, Lira VA, Meyerholz DK, Talley JJ, Adams CM. Ebert SM, et al. Among authors: dyle mc. J Biol Chem. 2015 Oct 16;290(42):25497-511. doi: 10.1074/jbc.M115.681445. Epub 2015 Sep 3. J Biol Chem. 2015. PMID: 26338703 Free PMC article.
16 results