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Amplification techniques and diagnosis of prion diseases.
Brandel JP, Culeux A, Grznarova K, Levavasseur E, Lamy P, Privat N, Welaratne A, Denouel A, Laplanche JL, Haik S. Brandel JP, et al. Among authors: laplanche jl. Rev Neurol (Paris). 2019 Sep-Oct;175(7-8):458-463. doi: 10.1016/j.neurol.2019.06.002. Epub 2019 Jul 8. Rev Neurol (Paris). 2019. PMID: 31296398 Review.
Quantification of surviving cerebellar granule neurones and abnormal prion protein (PrPSc) deposition in sporadic Creutzfeldt-Jakob disease supports a pathogenic role for small PrPSc deposits common to the various molecular subtypes.
Faucheux BA, Morain E, Diouron V, Brandel JP, Salomon D, Sazdovitch V, Privat N, Laplanche JL, Hauw JJ, Haïk S. Faucheux BA, et al. Among authors: laplanche jl. Neuropathol Appl Neurobiol. 2011 Aug;37(5):500-12. doi: 10.1111/j.1365-2990.2011.01179.x. Neuropathol Appl Neurobiol. 2011. PMID: 21450052
Substitutions at residue 211 in the prion protein drive a switch between CJD and GSS syndrome, a new mechanism governing inherited neurodegenerative disorders.
Peoc'h K, Levavasseur E, Delmont E, De Simone A, Laffont-Proust I, Privat N, Chebaro Y, Chapuis C, Bedoucha P, Brandel JP, Laquerriere A, Kemeny JL, Hauw JJ, Borg M, Rezaei H, Derreumaux P, Laplanche JL, Haïk S. Peoc'h K, et al. Among authors: laplanche jl. Hum Mol Genet. 2012 Dec 15;21(26):5417-28. doi: 10.1093/hmg/dds377. Epub 2012 Sep 10. Hum Mol Genet. 2012. PMID: 22965875
Detection of prions in the plasma of presymptomatic and symptomatic patients with variant Creutzfeldt-Jakob disease.
Bougard D, Brandel JP, Bélondrade M, Béringue V, Segarra C, Fleury H, Laplanche JL, Mayran C, Nicot S, Green A, Welaratne A, Narbey D, Fournier-Wirth C, Knight R, Will R, Tiberghien P, Haïk S, Coste J. Bougard D, et al. Among authors: laplanche jl. Sci Transl Med. 2016 Dec 21;8(370):370ra182. doi: 10.1126/scitranslmed.aag1257. Sci Transl Med. 2016. PMID: 28003547
220 results