Smith P - Search Results

1

Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys.

Theil D, Smith P, Huck C, Gilbart Y, Kakarieka A, Leppert D, Rauld C, Schmid C, Baumgartner R, Stuber N, Cordoba F, Dubost V, Darribat K, Jivkov M, Frieauff W, Kneuer R, Stoeckli M, Reinker S, Mansfield K, Carballido JM, Couttet P, Weckbecker G. Theil D, et al. Among authors: smith p. Front Immunol. 2019 Jun 20;10:1340. doi: 10.3389/fimmu.2019.01340. eCollection 2019. Front Immunol. 2019. PMID: 31281311 Free PMC article.

2

Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.

Bornancin F, Renner F, Touil R, Sic H, Kolb Y, Touil-Allaoui I, Rush JS, Smith PA, Bigaud M, Junker-Walker U, Burkhart C, Dawson J, Niwa S, Katopodis A, Nuesslein-Hildesheim B, Weckbecker G, Zenke G, Kinzel B, Traggiai E, Brenner D, Brüstle A, St Paul M, Zamurovic N, McCoy KD, Rolink A, Régnier CH, Mak TW, Ohashi PS, Patel DD, Calzascia T. Bornancin F, et al. J Immunol. 2015 Apr 15;194(8):3723-34. doi: 10.4049/jimmunol.1402254. Epub 2015 Mar 11. J Immunol. 2015. PMID: 25762782

3

Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945.

Beckmann N, Giorgetti E, Neuhaus A, Zurbruegg S, Accart N, Smith P, Perdoux J, Perrot L, Nash M, Desrayaud S, Wipfli P, Frieauff W, Shimshek DR. Beckmann N, et al. Among authors: smith p. Acta Neuropathol Commun. 2018 Feb 15;6(1):9. doi: 10.1186/s40478-018-0510-8. Acta Neuropathol Commun. 2018. PMID: 29448957 Free PMC article.

4

Fingolimod inhibits brain atrophy and promotes brain-derived neurotrophic factor in an animal model of multiple sclerosis.

Smith PA, Schmid C, Zurbruegg S, Jivkov M, Doelemeyer A, Theil D, Dubost V, Beckmann N. Smith PA, et al. J Neuroimmunol. 2018 May 15;318:103-113. doi: 10.1016/j.jneuroim.2018.02.016. Epub 2018 Mar 3. J Neuroimmunol. 2018. PMID: 29530550

5

Low-Dose Subcutaneous Anti-CD20 Treatment Depletes Disease Relevant B Cell Subsets and Attenuates Neuroinflammation.

Huck C, Leppert D, Wegert V, Schmid C, Dunn R, Weckbecker G, Smith PA. Huck C, et al. J Neuroimmune Pharmacol. 2019 Dec;14(4):709-719. doi: 10.1007/s11481-019-09872-z. Epub 2019 Aug 21. J Neuroimmune Pharmacol. 2019. PMID: 31435856

6

Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis.

Nuesslein-Hildesheim B, Ferrero E, Schmid C, Huck C, Smith P, Tisserand S, Rubert J, Bornancin F, Eichlisberger D, Cenni B. Nuesslein-Hildesheim B, et al. Among authors: smith p. J Neuroinflammation. 2023 Aug 26;20(1):194. doi: 10.1186/s12974-023-02877-9. J Neuroinflammation. 2023. PMID: 37633912 Free PMC article.

7

A potent and selective S1P(1) antagonist with efficacy in experimental autoimmune encephalomyelitis.

Quancard J, Bollbuck B, Janser P, Angst D, Berst F, Buehlmayer P, Streiff M, Beerli C, Brinkmann V, Guerini D, Smith PA, Seabrook TJ, Traebert M, Seuwen K, Hersperger R, Bruns C, Bassilana F, Bigaud M. Quancard J, et al. Among authors: smith pa. Chem Biol. 2012 Sep 21;19(9):1142-51. doi: 10.1016/j.chembiol.2012.07.016. Chem Biol. 2012. PMID: 22999882

8

PET Imaging of T Cells: Target Identification and Feasibility Assessment.

Auberson YP, Briard E, Rudolph B, Kaupmann K, Smith P, Oberhauser B. Auberson YP, et al. Among authors: smith p. ChemMedChem. 2018 Aug 10;13(15):1566-1579. doi: 10.1002/cmdc.201800241. Epub 2018 Jul 2. ChemMedChem. 2018. PMID: 29856125

9

The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration.

Bianchi B, Smith PA, Abriel H. Bianchi B, et al. Mol Brain. 2018 Jul 11;11(1):41. doi: 10.1186/s13041-018-0385-4. Mol Brain. 2018. PMID: 29996905 Free PMC article.

10

Potent activity of polymyxin B is associated with long-lived super-stoichiometric accumulation mediated by weak-affinity binding to lipid A.

Buchholz KR, Reichelt M, Johnson MC, Robinson SJ, Smith PA, Rutherford ST, Quinn JG. Buchholz KR, et al. Among authors: smith pa. Nat Commun. 2024 Jun 3;15(1):4733. doi: 10.1038/s41467-024-49200-5. Nat Commun. 2024. PMID: 38830951

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