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Discovery and pharmacological evaluation of indole derivatives as potent and selective RORγt inverse agonist for multiple autoimmune conditions.
Bioorg Med Chem Lett. 2019 Aug 15;29(16):2208-2217. doi: 10.1016/j.bmcl.2019.06.044. Epub 2019 Jun 22.
Bioorg Med Chem Lett. 2019.
PMID: 31272795
Discovery and evaluation of 1H-pyrrolo[2,3-b]pyridine based selective and reversible small molecule BTK inhibitors for the treatment of rheumatoid arthritis.
Thakkar M, Bhuniya D, Kaduskar R, Mengawade T, Naik K, Salunkhe V, Bhalerao A, Kurhade S, Mavinahalli J, Jain V, Petla R, Avaragolla S, Ray S, Rouduri S, Dhanave A, De S, Pathade V, Tambe A, Raje AA, Madgula V, Joshi S, Nadeem A, Bala M, Umrani D, Hariharan N, Kulkarni B, Mookhtiar KA.
Thakkar M, et al. Among authors: rouduri s.
Bioorg Med Chem Lett. 2017 Apr 15;27(8):1867-1873. doi: 10.1016/j.bmcl.2017.02.026. Epub 2017 Feb 22.
Bioorg Med Chem Lett. 2017.
PMID: 28279528
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Design, Synthesis of Novel, Potent, Selective, Orally Bioavailable Adenosine A2A Receptor Antagonists and Their Biological Evaluation.
Basu S, Barawkar DA, Thorat S, Shejul YD, Patel M, Naykodi M, Jain V, Salve Y, Prasad V, Chaudhary S, Ghosh I, Bhat G, Quraishi A, Patil H, Ansari S, Menon S, Unadkat V, Thakare R, Seervi MS, Meru AV, De S, Bhamidipati RK, Rouduri SR, Palle VP, Chug A, Mookhtiar KA.
Basu S, et al. Among authors: rouduri sr.
J Med Chem. 2017 Jan 26;60(2):681-694. doi: 10.1021/acs.jmedchem.6b01584. Epub 2017 Jan 17.
J Med Chem. 2017.
PMID: 28055204
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Discovery of Potent and Selective A2A Antagonists with Efficacy in Animal Models of Parkinson's Disease and Depression.
Basu S, Barawkar DA, Ramdas V, Naykodi M, Shejul YD, Patel M, Thorat S, Panmand A, Kashinath K, Bonagiri R, Prasad V, Bhat G, Quraishi A, Chaudhary S, Magdum A, Meru AV, Ghosh I, Bhamidipati RK, Raje AA, Madgula VLM, De S, Rouduri SR, Palle VP, Chugh A, Hariharan N, Mookhtiar KA.
Basu S, et al. Among authors: rouduri sr.
ACS Med Chem Lett. 2017 Jul 5;8(8):835-840. doi: 10.1021/acsmedchemlett.7b00175. eCollection 2017 Aug 10.
ACS Med Chem Lett. 2017.
PMID: 28835798
Free PMC article.
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A2B adenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives.
Basu S, Barawkar DA, Ramdas V, Waman Y, Patel M, Panmand A, Kumar S, Thorat S, Bonagiri R, Jadhav D, Mukhopadhyay P, Prasad V, Reddy BS, Goswami A, Chaturvedi S, Menon S, Quraishi A, Ghosh I, Dusange S, Paliwal S, Kulkarni A, Karande V, Thakre R, Bedse G, Rouduri S, Gundu J, Palle VP, Chugh A, Mookhtiar KA.
Basu S, et al. Among authors: rouduri s.
Eur J Med Chem. 2017 Feb 15;127:986-996. doi: 10.1016/j.ejmech.2016.11.007. Epub 2016 Nov 8.
Eur J Med Chem. 2017.
PMID: 27842891
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Design and synthesis of novel xanthine derivatives as potent and selective A2B adenosine receptor antagonists for the treatment of chronic inflammatory airway diseases.
Basu S, Barawkar DA, Ramdas V, Patel M, Waman Y, Panmand A, Kumar S, Thorat S, Naykodi M, Goswami A, Reddy BS, Prasad V, Chaturvedi S, Quraishi A, Menon S, Paliwal S, Kulkarni A, Karande V, Ghosh I, Mustafa S, De S, Jain V, Banerjee ER, Rouduri SR, Palle VP, Chugh A, Mookhtiar KA.
Basu S, et al. Among authors: rouduri sr.
Eur J Med Chem. 2017 Jul 7;134:218-229. doi: 10.1016/j.ejmech.2017.04.014. Epub 2017 Apr 12.
Eur J Med Chem. 2017.
PMID: 28415011
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GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.
Goodwin JM, Walkup WG 4th, Hooper K, Li T, Kishi-Itakura C, Ng A, Lehmberg T, Jha A, Kommineni S, Fletcher K, Garcia-Fortanet J, Fan Y, Tang Q, Wei M, Agrawal A, Budhe SR, Rouduri SR, Baird D, Saunders J, Kiselar J, Chance MR, Ballabio A, Appleton BA, Brumell JH, Florey O, Murphy LO.
Goodwin JM, et al. Among authors: rouduri sr.
Sci Adv. 2021 Oct;7(40):eabj2485. doi: 10.1126/sciadv.abj2485. Epub 2021 Oct 1.
Sci Adv. 2021.
PMID: 34597140
Free PMC article.
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