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Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
Albrecht W, Kappenberg F, Brecklinghaus T, Stoeber R, Marchan R, Zhang M, Ebbert K, Kirschner H, Grinberg M, Leist M, Moritz W, Cadenas C, Ghallab A, Reinders J, Vartak N, van Thriel C, Golka K, Tolosa L, Castell JV, Damm G, Seehofer D, Lampen A, Braeuning A, Buhrke T, Behr AC, Oberemm A, Gu X, Kittana N, van de Water B, Kreiling R, Fayyaz S, van Aerts L, Smedsrød B, Ellinger-Ziegelbauer H, Steger-Hartmann T, Gundert-Remy U, Zeigerer A, Ullrich A, Runge D, Lee SML, Schiergens TS, Kuepfer L, Aguayo-Orozco A, Sachinidis A, Edlund K, Gardner I, Rahnenführer J, Hengstler JG. Albrecht W, et al. Among authors: oberemm a. Arch Toxicol. 2019 Jun;93(6):1609-1637. doi: 10.1007/s00204-019-02492-9. Epub 2019 Jun 27. Arch Toxicol. 2019. PMID: 31250071
The use of toxicodynamics in risk assessment.
Heinrich-Hirsch B, Madle S, Oberemm A, Gundert-Remy U. Heinrich-Hirsch B, et al. Among authors: oberemm a. Toxicol Lett. 2001 Mar 31;120(1-3):131-41. doi: 10.1016/s0378-4274(01)00291-0. Toxicol Lett. 2001. PMID: 11323170
The use of in vitro data in risk assessment.
Bernauer U, Oberemm A, Madle S, Gundert-Remy U. Bernauer U, et al. Among authors: oberemm a. Basic Clin Pharmacol Toxicol. 2005 Mar;96(3):176-81. doi: 10.1111/j.1742-7843.2005.pto960306.x. Basic Clin Pharmacol Toxicol. 2005. PMID: 15733212 Free article. Review.
How can toxicogenomics inform risk assessment?
Oberemm A, Onyon L, Gundert-Remy U. Oberemm A, et al. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):592-8. doi: 10.1016/j.taap.2005.01.044. Toxicol Appl Pharmacol. 2005. PMID: 15990130 Review.
Primary rat hepatocytes as in vitro system for gene expression studies: comparison of sandwich, Matrigel and 2D cultures.
Schug M, Heise T, Bauer A, Storm D, Blaszkewicz M, Bedawy E, Brulport M, Geppert B, Hermes M, Föllmann W, Rapp K, Maccoux L, Schormann W, Appel KE, Oberemm A, Gundert-Remy U, Hengstler JG. Schug M, et al. Among authors: oberemm a. Arch Toxicol. 2008 Dec;82(12):923-31. doi: 10.1007/s00204-008-0375-x. Epub 2008 Nov 6. Arch Toxicol. 2008. PMID: 18987846
Toxicogenomic analysis of N-nitrosomorpholine induced changes in rat liver: comparison of genomic and proteomic responses and anchoring to histopathological parameters.
Oberemm A, Ahr HJ, Bannasch P, Ellinger-Ziegelbauer H, Glückmann M, Hellmann J, Ittrich C, Kopp-Schneider A, Kramer PJ, Krause E, Kröger M, Kiss E, Richter-Reichhelm HB, Scholz G, Seemann K, Weimer M, Gundert-Remy U. Oberemm A, et al. Toxicol Appl Pharmacol. 2009 Dec 1;241(2):230-45. doi: 10.1016/j.taap.2009.08.020. Epub 2009 Aug 28. Toxicol Appl Pharmacol. 2009. PMID: 19716841
In vitro - in vivo correlation of gene expression alterations induced by liver carcinogens.
Heise T, Schug M, Storm D, Ellinger-Ziegelbauer H, Ahr HJ, Hellwig B, Rahnenfuhrer J, Ghallab A, Guenther G, Sisnaiske J, Reif R, Godoy P, Mielke H, Gundert-Remy U, Lampen A, Oberemm A, Hengstler JG. Heise T, et al. Among authors: oberemm a. Curr Med Chem. 2012;19(11):1721-30. doi: 10.2174/092986712799945049. Curr Med Chem. 2012. PMID: 22414088
37 results