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Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
Albrecht W, Kappenberg F, Brecklinghaus T, Stoeber R, Marchan R, Zhang M, Ebbert K, Kirschner H, Grinberg M, Leist M, Moritz W, Cadenas C, Ghallab A, Reinders J, Vartak N, van Thriel C, Golka K, Tolosa L, Castell JV, Damm G, Seehofer D, Lampen A, Braeuning A, Buhrke T, Behr AC, Oberemm A, Gu X, Kittana N, van de Water B, Kreiling R, Fayyaz S, van Aerts L, Smedsrød B, Ellinger-Ziegelbauer H, Steger-Hartmann T, Gundert-Remy U, Zeigerer A, Ullrich A, Runge D, Lee SML, Schiergens TS, Kuepfer L, Aguayo-Orozco A, Sachinidis A, Edlund K, Gardner I, Rahnenführer J, Hengstler JG. Albrecht W, et al. Among authors: behr ac. Arch Toxicol. 2019 Jun;93(6):1609-1637. doi: 10.1007/s00204-019-02492-9. Epub 2019 Jun 27. Arch Toxicol. 2019. PMID: 31250071
It takes more than a coating to get nanoparticles through the intestinal barrier in vitro.
Lichtenstein D, Ebmeyer J, Meyer T, Behr AC, Kästner C, Böhmert L, Juling S, Niemann B, Fahrenson C, Selve S, Thünemann AF, Meijer J, Estrela-Lopis I, Braeuning A, Lampen A. Lichtenstein D, et al. Among authors: behr ac. Eur J Pharm Biopharm. 2017 Sep;118:21-29. doi: 10.1016/j.ejpb.2016.12.004. Epub 2016 Dec 18. Eur J Pharm Biopharm. 2017. PMID: 27993735
Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.
Louro H, Vettorazzi A, López de Cerain A, Spyropoulou A, Solhaug A, Straumfors A, Behr AC, Mertens B, Žegura B, Fæste CK, Ndiaye D, Spilioti E, Varga E, Dubreil E, Borsos E, Crudo F, Eriksen GS, Snapkow I, Henri J, Sanders J, Machera K, Gaté L, Le Hegarat L, Novak M, Smith NM, Krapf S, Hager S, Fessard V, Kohl Y, Silva MJ, Dirven H, Dietrich J, Marko D. Louro H, et al. Among authors: behr ac. Arch Toxicol. 2024 Feb;98(2):425-469. doi: 10.1007/s00204-023-03636-8. Epub 2023 Dec 26. Arch Toxicol. 2024. PMID: 38147116 Free PMC article. Review.