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Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3).
Wang X, Gocek E, Novik V, Harrison JS, Danilenko M, Studzinski GP. Wang X, et al. Among authors: studzinski gp. Cell Cycle. 2010 Nov 15;9(22):4542-51. doi: 10.4161/cc.9.22.13790. Epub 2010 Nov 15. Cell Cycle. 2010. PMID: 21084834 Free PMC article.
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