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DEK is required for homologous recombination repair of DNA breaks.
Smith EA, Gole B, Willis NA, Soria R, Starnes LM, Krumpelbeck EF, Jegga AG, Ali AM, Guo H, Meetei AR, Andreassen PR, Kappes F, Vinnedge LM, Daniel JA, Scully R, Wiesmüller L, Wells SI. Smith EA, et al. Among authors: guo h. Sci Rep. 2017 Mar 20;7:44662. doi: 10.1038/srep44662. Sci Rep. 2017. PMID: 28317934 Free PMC article.
Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling.
Capitano ML, Mor-Vaknin N, Saha AK, Cooper S, Legendre M, Guo H, Contreras-Galindo R, Kappes F, Sartor MA, Lee CT, Huang X, Markovitz DM, Broxmeyer HE. Capitano ML, et al. Among authors: guo h. J Clin Invest. 2019 May 20;129(6):2555-2570. doi: 10.1172/JCI127460. eCollection 2019 May 20. J Clin Invest. 2019. PMID: 31107242 Free PMC article.
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1.
Cifdaloz M, Osterloh L, Graña O, Riveiro-Falkenbach E, Ximénez-Embún P, Muñoz J, Tejedo C, Calvo TG, Karras P, Olmeda D, Miñana B, Gómez-López G, Cañon E, Eyras E, Guo H, Kappes F, Ortiz-Romero PL, Rodríguez-Peralto JL, Megías D, Valcárcel J, Soengas MS. Cifdaloz M, et al. Among authors: guo h. Nat Commun. 2017 Dec 21;8(1):2249. doi: 10.1038/s41467-017-02353-y. Nat Commun. 2017. PMID: 29269732 Free PMC article.
Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation.
Tripathi P, Guo H, Dreser A, Yamoah A, Sechi A, Jesse CM, Katona I, Doukas P, Nikolin S, Ernst S, Aronica E, Glaß H, Hermann A, Steinbusch H, Feller AC, Bergmann M, Jaarsma D, Weis J, Goswami A. Tripathi P, et al. Among authors: guo h. Cell Death Dis. 2021 May 10;12(5):466. doi: 10.1038/s41419-021-03710-y. Cell Death Dis. 2021. PMID: 33972508 Free PMC article.
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