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A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism.
Ptacin JL, Ma L, Caffaro CE, Acuff NV, Germar K, Severy P, Qu Y, Vela JL, Cai X, San Jose KM, Aerni HR, Chen DB, Esche E, Ismaili TK, Herman R, Pavlova Y, Pena MJ, Nguyen J, Koriazova LK, Shawver LK, Joseph IB, Mooney J, Peakman M, Milla ME. Ptacin JL, et al. Among authors: germar k. Commun Med (Lond). 2024 Mar 26;4(1):58. doi: 10.1038/s43856-024-00485-z. Commun Med (Lond). 2024. PMID: 38532017 Free PMC article.
Integration of needle-free jet injection with advanced electroporation delivery enhances the magnitude, kinetics, and persistence of engineered DNA vaccine induced immune responses.
Jiang J, Ramos SJ, Bangalore P, Fisher P, Germar K, Lee BK, Williamson D, Kemme A, Schade E, McCoy J, Muthumani K, Weiner DB, Humeau LM, Broderick KE. Jiang J, et al. Among authors: germar k. Vaccine. 2019 Jun 27;37(29):3832-3839. doi: 10.1016/j.vaccine.2019.05.054. Epub 2019 Jun 4. Vaccine. 2019. PMID: 31174938 Free article.
BOB.1 controls memory B-cell fate in the germinal center reaction.
Levels MJ, Fehres CM, van Baarsen LGM, van Uden NOP, Germar K, O'Toole TG, Blijdorp ICJ, Semmelink JF, Doorenspleet ME, Bakker AQ, Krasavin M, Tomilin A, Brouard S, Spits H, Baeten DLP, Yeremenko NG. Levels MJ, et al. Among authors: germar k. J Autoimmun. 2019 Jul;101:131-144. doi: 10.1016/j.jaut.2019.04.011. Epub 2019 Apr 30. J Autoimmun. 2019. PMID: 31053401 Free article.
Generation and Characterization of Anti-Citrullinated Protein Antibody-Producing B Cell Clones From Rheumatoid Arthritis Patients.
Germar K, Fehres CM, Scherer HU, van Uden N, Pollastro S, Yeremenko N, Hansson M, Kerkman PF, van der Voort EIH, Reed E, Maassen H, Kwakkenbos MJ, Bakker AQ, Klareskog L, Malmström V, de Vries N, Toes REM, Lundberg K, Spits H, Baeten DL. Germar K, et al. Arthritis Rheumatol. 2019 Mar;71(3):340-350. doi: 10.1002/art.40739. Epub 2019 Feb 2. Arthritis Rheumatol. 2019. PMID: 30277007
Interleukin-12 and -23 Control Plasticity of CD127(+) Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria.
Bernink JH, Krabbendam L, Germar K, de Jong E, Gronke K, Kofoed-Nielsen M, Munneke JM, Hazenberg MD, Villaudy J, Buskens CJ, Bemelman WA, Diefenbach A, Blom B, Spits H. Bernink JH, et al. Among authors: germar k. Immunity. 2015 Jul 21;43(1):146-60. doi: 10.1016/j.immuni.2015.06.019. Epub 2015 Jul 14. Immunity. 2015. PMID: 26187413 Free article.
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