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Deferasirox reduces oxidative DNA damage in bone marrow cells from myelodysplastic patients and improves their differentiation capacity.
Jiménez-Solas T, López-Cadenas F, Aires-Mejía I, Caballero-Berrocal JC, Ortega R, Redondo AM, Sánchez-Guijo F, Muntión S, García-Martín L, Albarrán B, Alonso JM, Del Cañizo C, Hernández-Hernández Á, Díez-Campelo M. Jiménez-Solas T, et al. Among authors: ortega r. Br J Haematol. 2019 Oct;187(1):93-104. doi: 10.1111/bjh.16013. Epub 2019 Jun 6. Br J Haematol. 2019. PMID: 31172513 Free article. Clinical Trial.
MSC surface markers (CD44, CD73, and CD90) can identify human MSC-derived extracellular vesicles by conventional flow cytometry.
L Ramos T, Sánchez-Abarca LI, Muntión S, Preciado S, Puig N, López-Ruano G, Hernández-Hernández Á, Redondo A, Ortega R, Rodríguez C, Sánchez-Guijo F, del Cañizo C. L Ramos T, et al. Among authors: ortega r. Cell Commun Signal. 2016 Jan 12;14:2. doi: 10.1186/s12964-015-0124-8. Cell Commun Signal. 2016. PMID: 26754424 Free PMC article.
HDAC8 overexpression in mesenchymal stromal cells from JAK2+ myeloproliferative neoplasms: a new therapeutic target?
Ramos TL, Sánchez-Abarca LI, Redondo A, Hernández-Hernández Á, Almeida AM, Puig N, Rodríguez C, Ortega R, Preciado S, Rico A, Muntión S, Porras JRG, Del Cañizo C, Sánchez-Guijo F. Ramos TL, et al. Among authors: ortega r. Oncotarget. 2017 Apr 25;8(17):28187-28202. doi: 10.18632/oncotarget.15969. Oncotarget. 2017. PMID: 28390197 Free PMC article.
Mesenchymal stromal cells (MSC) from JAK2+ myeloproliferative neoplasms differ from normal MSC and contribute to the maintenance of neoplastic hematopoiesis.
Ramos TL, Sánchez-Abarca LI, Rosón-Burgo B, Redondo A, Rico A, Preciado S, Ortega R, Rodríguez C, Muntión S, Hernández-Hernández Á, De Las Rivas J, González M, González Porras JR, Del Cañizo C, Sánchez-Guijo F. Ramos TL, et al. Among authors: ortega r. PLoS One. 2017 Aug 10;12(8):e0182470. doi: 10.1371/journal.pone.0182470. eCollection 2017. PLoS One. 2017. PMID: 28796790 Free PMC article.
Mesenchymal Stromal Cell Irradiation Interferes with the Adipogenic/Osteogenic Differentiation Balance and Improves Their Hematopoietic-Supporting Ability.
Preciado S, Muntión S, Rico A, Pérez-Romasanta LA, Ramos TL, Ortega R, Borrajo J, Corchete LA, Rodríguez C, Díez-Campelo M, Sánchez-Abarca LI, Del Cañizo MC, Sánchez-Guijo F. Preciado S, et al. Among authors: ortega r. Biol Blood Marrow Transplant. 2018 Mar;24(3):443-451. doi: 10.1016/j.bbmt.2017.11.007. Epub 2017 Nov 16. Biol Blood Marrow Transplant. 2018. PMID: 29155314 Free article.
NADP+ binding to the regulatory subunit of methionine adenosyltransferase II increases intersubunit binding affinity in the hetero-trimer.
González B, Garrido F, Ortega R, Martínez-Júlvez M, Revilla-Guarinos A, Pérez-Pertejo Y, Velázquez-Campoy A, Sanz-Aparicio J, Pajares MA. González B, et al. Among authors: ortega r. PLoS One. 2012;7(11):e50329. doi: 10.1371/journal.pone.0050329. Epub 2012 Nov 26. PLoS One. 2012. PMID: 23189196 Free PMC article.
Combining loop with thiazide diuretics in patients discharged home after a heart failure decompensation: Association with 30-day outcomes.
Miró Ò, Núñez J, Trullàs JC, Lopez-Ayala P, Llauger L, Alquézar-Arbé A, Miñana G, Mollar A, de la Espriella R, Lorenzo M, Jacob J, Espinosa B, Garcés-Horna V, Aguirre A, Fortuny MJ, Martínez-Nadal G, Gil V, Mueller C, Llorens P; ICA-SEMES; INCLIVA; ALCALOTIC research groups. Miró Ò, et al. Eur J Intern Med. 2024 May 18:S0953-6205(24)00213-9. doi: 10.1016/j.ejim.2024.05.009. Online ahead of print. Eur J Intern Med. 2024. PMID: 38763846
Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation.
Nguyen LL, Watson ZL, Ortega R, Woodruff ER, Jordan KR, Iwanaga R, Yamamoto TM, Bailey CA, To F, Jeong AD, Guntupalli SR, Behbakht K, Gibaja V, Arnoult N, Cocozaki A, Chuong EB, Bitler BG. Nguyen LL, et al. Among authors: ortega r. Mol Cancer Ther. 2024 May 8. doi: 10.1158/1535-7163.MCT-23-0613. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38714351
886 results