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NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models.
Bahn G, Park JS, Yun UJ, Lee YJ, Choi Y, Park JS, Baek SH, Choi BY, Cho YS, Kim HK, Han J, Sul JH, Baik SH, Lim J, Wakabayashi N, Bae SH, Han JW, Arumugam TV, Mattson MP, Jo DG. Bahn G, et al. Among authors: wakabayashi n. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12516-12523. doi: 10.1073/pnas.1819541116. Epub 2019 Jun 4. Proc Natl Acad Sci U S A. 2019. PMID: 31164420 Free PMC article.
Crosstalk between Nrf2 and Notch signaling.
Wakabayashi N, Chartoumpekis DV, Kensler TW. Wakabayashi N, et al. Free Radic Biol Med. 2015 Nov;88(Pt B):158-167. doi: 10.1016/j.freeradbiomed.2015.05.017. Epub 2015 May 21. Free Radic Biol Med. 2015. PMID: 26003520 Free PMC article. Review.
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants.
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, Talalay P. Dinkova-Kostova AT, et al. Among authors: wakabayashi n. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11908-13. doi: 10.1073/pnas.172398899. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193649 Free PMC article.
387 results