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Platelet-Rich Emboli in Cerebral Large Vessel Occlusion Are Associated With a Large Artery Atherosclerosis Source.
Fitzgerald S, Dai D, Wang S, Douglas A, Kadirvel R, Layton KF, Thacker IC, Gounis MJ, Chueh JY, Puri AS, Almekhlafi M, Demchuk AM, Hanel RA, Sauvageau E, Aghaebrahim A, Yoo AJ, Kvamme P, M Pereira V, Kayan Y, Delgado Almandoz JE, Nogueira RG, Rabinstein AA, Kallmes DF, Doyle KM, Brinjikji W. Fitzgerald S, et al. Among authors: douglas a. Stroke. 2019 Jul;50(7):1907-1910. doi: 10.1161/STROKEAHA.118.024543. Epub 2019 May 29. Stroke. 2019. PMID: 31138084 Free PMC article.
Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT.
Fitzgerald ST, Wang S, Dai D, Douglas A, Kadirvel R, Gounis MJ, Chueh J, Puri AS, Layton KF, Thacker IC, Hanel RA, Sauvageau E, Aghaebrahim A, Almekhlafi MA, Demchuk AM, Nogueira RG, Pereira VM, Kvamme P, Kayan Y, Delgado Almandoz JE, Yoo AJ, Kallmes DF, Doyle KM, Brinjikji W. Fitzgerald ST, et al. Among authors: douglas a. J Neurointerv Surg. 2019 Nov;11(11):1145-1149. doi: 10.1136/neurintsurg-2018-014637. Epub 2019 Apr 5. J Neurointerv Surg. 2019. PMID: 30952688 Free PMC article.
Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes.
Douglas A, Fitzgerald S, Mereuta OM, Rossi R, O'Leary S, Pandit A, McCarthy R, Gilvarry M, Holmegaard L, Abrahamsson M, Jerndal M, Dehlfors N, Brennan P, Power S, O'Hare A, Griffin E, Kallmes DF, Brinjikji W, Szikora I, Tatlisumak T, Rentzos A, Thornton J, Doyle K. Douglas A, et al. J Neurointerv Surg. 2020 Jun;12(6):557-562. doi: 10.1136/neurintsurg-2019-015410. Epub 2019 Nov 4. J Neurointerv Surg. 2020. PMID: 31685695
Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots.
Fitzgerald S, Wang S, Dai D, Murphree DH Jr, Pandit A, Douglas A, Rizvi A, Kadirvel R, Gilvarry M, McCarthy R, Stritt M, Gounis MJ, Brinjikji W, Kallmes DF, Doyle KM. Fitzgerald S, et al. Among authors: douglas a. PLoS One. 2019 Dec 5;14(12):e0225841. doi: 10.1371/journal.pone.0225841. eCollection 2019. PLoS One. 2019. PMID: 31805096 Free PMC article.
The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does not influence revascularization outcome.
Rossi R, Fitzgerald S, Molina S, Mereuta OM, Douglas A, Pandit A, Santos AMS, Murphy B, Alderson J, Brennan P, Power S, O'Hare A, Gilvarry M, McCarthy R, Psychogios K, Magoufis G, Tsivgoulis G, Nagy A, Vadász Á, Szikora I, Jood K, Redfors P, Nordanstig A, Ceder E, Dehlfors N, Dunker D, Tatlisumak T, Rentzos A, Thornton J, Doyle KM. Rossi R, et al. Among authors: douglas a. J Thromb Thrombolysis. 2021 Feb;51(2):545-551. doi: 10.1007/s11239-020-02279-1. Epub 2020 Sep 16. J Thromb Thrombolysis. 2021. PMID: 32936433 Free PMC article.
Dielectric profile of blood clots to inform ischemic stroke treatments.
Santorelli A, Fitzgerald S, Douglas A, Doyle K, O'Halloran M. Santorelli A, et al. Among authors: douglas a. Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:3723-3726. doi: 10.1109/EMBC44109.2020.9175387. Annu Int Conf IEEE Eng Med Biol Soc. 2020. PMID: 33018810
Large Artery Atherosclerotic Clots are Larger than Clots of other Stroke Etiologies and have Poorer Recanalization rates.
Fitzgerald S, Rossi R, Mereuta OM, Molina S, Okolo A, Douglas A, Jabrah D, Pandit A, McCarthy R, Gilvarry M, Ceder E, Dehlfors N, Dunker D, Nordanstig A, Redfors P, Jood K, Magoufis G, Psychogios K, Tsivgoulis G, Alderson J, O'Hare A, Power S, Brennan P, Nagy A, Vadász Á, Brinjikji W, Kallmes D, Szikora I, Tatlisumak T, Rentzos A, Thornton J, Doyle KM. Fitzgerald S, et al. Among authors: douglas a. J Stroke Cerebrovasc Dis. 2021 Jan;30(1):105463. doi: 10.1016/j.jstrokecerebrovasdis.2020.105463. Epub 2020 Nov 24. J Stroke Cerebrovasc Dis. 2021. PMID: 33242780 Free PMC article.
1,389 results