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Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors.
Gonzaga DTG, Oliveira FH, von Ranke NL, Pinho GQ, Salles JP, Bello ML, Rodrigues CR, Castro HC, de Souza HVCM, Reis CRC, Leme RPP, Mafra JCM, Pinheiro LCS, Hoelz LVB, Boechat N, Faria RX. Gonzaga DTG, et al. Among authors: pinheiro lcs. Front Chem. 2019 Apr 30;7:261. doi: 10.3389/fchem.2019.00261. eCollection 2019. Front Chem. 2019. PMID: 31134177 Free PMC article.
SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series.
Bernardino AM, Castro HC, Frugulhetti IC, Loureiro NI, Azevedo AR, Pinheiro LC, Souza TM, Giongo V, Passamani F, Magalhães UO, Albuquerque MG, Cabral LM, Rodrigues CR. Bernardino AM, et al. Bioorg Med Chem. 2008 Jan 1;16(1):313-21. doi: 10.1016/j.bmc.2007.09.032. Epub 2007 Sep 22. Bioorg Med Chem. 2008. PMID: 17937990
Identification of a potential lead structure for designing new antimicrobials to treat infections caused by Staphylococcus epidermidis-resistant strains.
Pinheiro LC, Abreu PA, Afonso IF, Leal B, Corrêa LC, Borges JC, Marques IP, Lourenço AL, Sathler P, dos Santos AL, Medeiros CA, Cabral LM, Júnior ML, Romeiro GA, Ferreira VF, Rodrigues CR, Castro HC, Bernardino AM. Pinheiro LC, et al. Curr Microbiol. 2008 Nov;57(5):463-8. doi: 10.1007/s00284-008-9234-5. Epub 2008 Sep 23. Curr Microbiol. 2008. PMID: 18810543
New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents.
Boechat N, Pinheiro LC, Silva TS, Aguiar AC, Carvalho AS, Bastos MM, Costa CC, Pinheiro S, Pinto AC, Mendonça JS, Dutra KD, Valverde AL, Santos-Filho OA, Ceravolo IP, Krettli AU. Boechat N, et al. Molecules. 2012 Jul 10;17(7):8285-302. doi: 10.3390/molecules17078285. Molecules. 2012. PMID: 22781441 Free PMC article.
Anti-Plasmodium falciparum activity of quinoline-sulfonamide hybrids.
Pinheiro LC, Boechat N, Ferreira Mde L, Júnior CC, Jesus AM, Leite MM, Souza NB, Krettli AU. Pinheiro LC, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5979-84. doi: 10.1016/j.bmc.2015.06.056. Epub 2015 Jul 2. Bioorg Med Chem. 2015. PMID: 26190461
23 results