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Synthetic molecules as P2X7 receptor antagonists: A medicinal chemistry update focusing the therapy of inflammatory diseases.
Eur J Pharmacol. 2023 Oct 15;957:175999. doi: 10.1016/j.ejphar.2023.175999. Epub 2023 Aug 22.
Eur J Pharmacol. 2023.
PMID: 37619787
Review.
Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors.
Gonzaga DTG, Oliveira FH, von Ranke NL, Pinho GQ, Salles JP, Bello ML, Rodrigues CR, Castro HC, de Souza HVCM, Reis CRC, Leme RPP, Mafra JCM, Pinheiro LCS, Hoelz LVB, Boechat N, Faria RX.
Gonzaga DTG, et al. Among authors: mafra jcm.
Front Chem. 2019 Apr 30;7:261. doi: 10.3389/fchem.2019.00261. eCollection 2019.
Front Chem. 2019.
PMID: 31134177
Free PMC article.
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Antinociceptive, anti-inflammatory and antipyretic effects of 1.5-diphenyl-1H-Pyrazole-3-carbohydrazide, a new heterocyclic pyrazole derivative.
Malvar Ddo C, Ferreira RT, de Castro RA, de Castro LL, Freitas AC, Costa EA, Florentino IF, Mafra JC, de Souza GE, Vanderlinde FA.
Malvar Ddo C, et al.
Life Sci. 2014 Jan 30;95(2):81-8. doi: 10.1016/j.lfs.2013.12.005. Epub 2013 Dec 17.
Life Sci. 2014.
PMID: 24355293
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