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Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin.
Powers JD, Yuan CC, McCabe KJ, Murray JD, Childers MC, Flint GV, Moussavi-Harami F, Mohran S, Castillo R, Zuzek C, Ma W, Daggett V, McCulloch AD, Irving TC, Regnier M. Powers JD, et al. Among authors: irving tc. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11502-11507. doi: 10.1073/pnas.1905028116. Epub 2019 May 20. Proc Natl Acad Sci U S A. 2019. PMID: 31110001 Free PMC article.
Reverse actin sliding triggers strong myosin binding that moves tropomyosin.
Bekyarova TI, Reedy MC, Baumann BA, Tregear RT, Ward A, Krzic U, Prince KM, Perz-Edwards RJ, Reconditi M, Gore D, Irving TC, Reedy MK. Bekyarova TI, et al. Among authors: irving tc. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10372-7. doi: 10.1073/pnas.0709877105. Epub 2008 Jul 25. Proc Natl Acad Sci U S A. 2008. PMID: 18658238 Free PMC article.
The length-tension curve in muscle depends on lattice spacing.
Williams CD, Salcedo MK, Irving TC, Regnier M, Daniel TL. Williams CD, et al. Among authors: irving tc. Proc Biol Sci. 2013 Sep 7;280(1766):20130697. doi: 10.1098/rspb.2013.0697. Print 2013 Sep 7. Proc Biol Sci. 2013. PMID: 23843386 Free PMC article.
Elastic proteins in the flight muscle of Manduca sexta.
Yuan CC, Ma W, Schemmel P, Cheng YS, Liu J, Tsaprailis G, Feldman S, Ayme Southgate A, Irving TC. Yuan CC, et al. Among authors: irving tc. Arch Biochem Biophys. 2015 Feb 15;568:16-27. doi: 10.1016/j.abb.2014.12.033. Epub 2015 Jan 17. Arch Biochem Biophys. 2015. PMID: 25602701 Free PMC article.
Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice.
Yuan CC, Kazmierczak K, Liang J, Kanashiro-Takeuchi R, Irving TC, Gomes AV, Wang Y, Burghardt TP, Szczesna-Cordary D. Yuan CC, et al. Among authors: irving tc. Cardiovasc Res. 2017 Aug 1;113(10):1124-1136. doi: 10.1093/cvr/cvx060. Cardiovasc Res. 2017. PMID: 28371863 Free PMC article.
186 results