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Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils.
Russo I, Kaganovich A, Ding J, Landeck N, Mamais A, Varanita T, Biosa A, Tessari I, Bubacco L, Greggio E, Cookson MR. Russo I, et al. Among authors: varanita t. Neurobiol Dis. 2019 Sep;129:67-78. doi: 10.1016/j.nbd.2019.05.012. Epub 2019 May 15. Neurobiol Dis. 2019. PMID: 31102768 Free PMC article.
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains.
Longhena F, Faustini G, Varanita T, Zaltieri M, Porrini V, Tessari I, Poliani PL, Missale C, Borroni B, Padovani A, Bubacco L, Pizzi M, Spano P, Bellucci A. Longhena F, et al. Among authors: varanita t. Brain Pathol. 2018 Nov;28(6):875-888. doi: 10.1111/bpa.12587. Epub 2018 Feb 23. Brain Pathol. 2018. PMID: 29330884 Free PMC article.
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.
Bachmann M, Rossa A, Varanita T, Fioretti B, Biasutto L, Milenkovic S, Checchetto V, Peruzzo R, Ahmad SA, Patel SH, Lukowski R, Edwards MJ, Ceccarelli M, Gulbins E, Zoratti M, Mattarei A, Szabo I. Bachmann M, et al. Among authors: varanita t. Cell Death Dis. 2022 Dec 20;13(12):1055. doi: 10.1038/s41419-022-05463-8. Cell Death Dis. 2022. PMID: 36539400 Free PMC article.
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