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Page 1
Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3.
Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, Ruvo M, Chambery A, Oblak M, Al-Obaidi MJ, Kaczmarski RS, Gabriel I, Oakervee HE, Kaiser MF, Wechalekar A, Benjamin R, Apperley JF, Auner HW, Franzoso G. Tornatore L, et al. Among authors: d andrea d, raimondo d. Toxicol Rep. 2019 Apr 19;6:369-379. doi: 10.1016/j.toxrep.2019.04.006. eCollection 2019. Toxicol Rep. 2019. PMID: 31080744 Free PMC article.
Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors.
Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA, Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G. Tornatore L, et al. Among authors: d andrea d, raimondo d. Cancer Cell. 2014 Oct 13;26(4):495-508. doi: 10.1016/j.ccr.2014.07.027. Cancer Cell. 2014. PMID: 25314077 Free PMC article.
Structural and biochemical insights of CypA and AIF interaction.
Farina B, Di Sorbo G, Chambery A, Caporale A, Leoni G, Russo R, Mascanzoni F, Raimondo D, Fattorusso R, Ruvo M, Doti N. Farina B, et al. Among authors: raimondo d. Sci Rep. 2017 Apr 25;7(1):1138. doi: 10.1038/s41598-017-01337-8. Sci Rep. 2017. PMID: 28442737 Free PMC article.
Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors.
Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA, Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G. Tornatore L, et al. Among authors: d andrea d, raimondo d. Cancer Cell. 2014 Dec 8;26(6):938. doi: 10.1016/j.ccell.2014.11.021. Epub 2014 Dec 8. Cancer Cell. 2014. PMID: 28898681 Free PMC article. No abstract available.
Probing the interaction interface of the GADD45β/MKK7 and MKK7/DTP3 complexes by chemical cross-linking mass spectrometry.
Rega C, Russo R, Focà A, Sandomenico A, Iaccarino E, Raimondo D, Milanetti E, Tornatore L, Franzoso G, Pedone PV, Ruvo M, Chambery A. Rega C, et al. Among authors: raimondo d. Int J Biol Macromol. 2018 Jul 15;114:114-123. doi: 10.1016/j.ijbiomac.2018.03.090. Epub 2018 Mar 20. Int J Biol Macromol. 2018. PMID: 29572137 Free PMC article.
Clinical proof of concept for a safe and effective NF-κB-targeting strategy in multiple myeloma.
Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, Ruvo M, Chambery A, Oblak M, Al-Obaidi MJ, Kaczmarski RS, Gabriel I, Oakervee HE, Kaiser MF, Wechalekar A, Benjamin R, Apperley JF, Auner HW, Franzoso G. Tornatore L, et al. Among authors: d andrea d, raimondo d. Br J Haematol. 2019 May;185(3):588-592. doi: 10.1111/bjh.15569. Epub 2018 Sep 26. Br J Haematol. 2019. PMID: 30255568 Free article. No abstract available.
Investigating the oxidative refolding mechanism of Cripto-1 CFC domain.
Iaccarino E, Sandomenico A, Corvino G, Focà G, Severino V, Russo R, Caporale A, Raimondo D, D'Abramo M, Alba J, Chambery A, Ruvo M. Iaccarino E, et al. Among authors: raimondo d, d abramo m. Int J Biol Macromol. 2019 Sep 15;137:1179-1189. doi: 10.1016/j.ijbiomac.2019.07.040. Epub 2019 Jul 8. Int J Biol Macromol. 2019. PMID: 31295488
Insights into the Interaction Mechanism of DTP3 with MKK7 by Using STD-NMR and Computational Approaches.
Sandomenico A, Di Rienzo L, Calvanese L, Iaccarino E, D'Auria G, Falcigno L, Chambery A, Russo R, Franzoso G, Tornatore L, D'Abramo M, Ruvo M, Milanetti E, Raimondo D. Sandomenico A, et al. Among authors: d auria g, raimondo d, d abramo m. Biomedicines. 2020 Dec 30;9(1):20. doi: 10.3390/biomedicines9010020. Biomedicines. 2020. PMID: 33396582 Free PMC article.
Bone density and genomic analysis unfold cold adaptation mechanisms of ancient inhabitants of Tierra del Fuego.
Watanabe M, Risi R, Tafuri MA, Silvestri V, D'Andrea D, Raimondo D, Rea S, Di Vincenzo F, Profico A, Tuccinardi D, Sciuto R, Basciani S, Mariani S, Lubrano C, Cinti S, Ottini L, Manzi G, Gnessi L. Watanabe M, et al. Among authors: d andrea d, raimondo d. Sci Rep. 2021 Dec 2;11(1):23290. doi: 10.1038/s41598-021-02783-1. Sci Rep. 2021. PMID: 34857816 Free PMC article.
450 results