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Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils.
Wilms H, Rosenstiel P, Romero-Ramos M, Arlt A, Schäfer H, Seegert D, Kahle PJ, Odoy S, Claasen JH, Holzknecht C, Brandenburg LO, Deuschl G, Schreiber S, Kirik D, Lucius R. Wilms H, et al. Among authors: claasen jh. Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):897-909. doi: 10.1177/039463200902200405. Int J Immunopathol Pharmacol. 2009. PMID: 20074453 Free article.
Inflammation is detrimental for neurogenesis in adult brain.
Ekdahl CT, Claasen JH, Bonde S, Kokaia Z, Lindvall O. Ekdahl CT, et al. Among authors: claasen jh. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13632-7. doi: 10.1073/pnas.2234031100. Epub 2003 Oct 27. Proc Natl Acad Sci U S A. 2003. PMID: 14581618 Free PMC article.
CXCR4 prevents dispersion of granule neuron precursors in the adult dentate gyrus.
Schultheiß C, Abe P, Hoffmann F, Mueller W, Kreuder AE, Schütz D, Haege S, Redecker C, Keiner S, Kannan S, Claasen JH, Pfrieger FW, Stumm R. Schultheiß C, et al. Among authors: claasen jh. Hippocampus. 2013 Dec;23(12):1345-58. doi: 10.1002/hipo.22180. Epub 2013 Sep 10. Hippocampus. 2013. PMID: 23929505