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The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators.
Tseng CC, Baillie G, Donvito G, Mustafa MA, Juola SE, Zanato C, Massarenti C, Dall'Angelo S, Harrison WTA, Lichtman AH, Ross RA, Zanda M, Greig IR. Tseng CC, et al. Among authors: zanda m. J Med Chem. 2019 May 23;62(10):5049-5062. doi: 10.1021/acs.jmedchem.9b00252. Epub 2019 May 14. J Med Chem. 2019. PMID: 31050898 Free PMC article.
A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives.
Lazzari P, Distinto R, Manca I, Baillie G, Murineddu G, Pira M, Falzoi M, Sani M, Morales P, Ross R, Zanda M, Jagerovic N, Pinna GA. Lazzari P, et al. Among authors: zanda m. Eur J Med Chem. 2016 Oct 4;121:194-208. doi: 10.1016/j.ejmech.2016.05.011. Epub 2016 May 6. Eur J Med Chem. 2016. PMID: 27240274
A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects.
Ignatowska-Jankowska BM, Baillie GL, Kinsey S, Crowe M, Ghosh S, Owens RA, Damaj IM, Poklis J, Wiley JL, Zanda M, Zanato C, Greig IR, Lichtman AH, Ross RA. Ignatowska-Jankowska BM, et al. Among authors: zanda m. Neuropsychopharmacology. 2015 Dec;40(13):2948-59. doi: 10.1038/npp.2015.148. Epub 2015 Jun 8. Neuropsychopharmacology. 2015. PMID: 26052038 Free PMC article.
[18F]ZCDD083: A PFKFB3-Targeted PET Tracer for Atherosclerotic Plaque Imaging.
De Dominicis C, Perrotta P, Dall'Angelo S, Wyffels L, Staelens S, De Meyer GRY, Zanda M. De Dominicis C, et al. Among authors: zanda m. ACS Med Chem Lett. 2020 Feb 19;11(5):933-939. doi: 10.1021/acsmedchemlett.9b00677. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435408 Free PMC article.
112 results