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The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators.
Tseng CC, Baillie G, Donvito G, Mustafa MA, Juola SE, Zanato C, Massarenti C, Dall'Angelo S, Harrison WTA, Lichtman AH, Ross RA, Zanda M, Greig IR. Tseng CC, et al. Among authors: lichtman ah. J Med Chem. 2019 May 23;62(10):5049-5062. doi: 10.1021/acs.jmedchem.9b00252. Epub 2019 May 14. J Med Chem. 2019. PMID: 31050898 Free PMC article.
In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569.
Gamage TF, Ignatowska-Jankowska BM, Wiley JL, Abdelrahman M, Trembleau L, Greig IR, Thakur GA, Tichkule R, Poklis J, Ross RA, Pertwee RG, Lichtman AH. Gamage TF, et al. Among authors: lichtman ah. Behav Pharmacol. 2014 Apr;25(2):182-5. doi: 10.1097/FBP.0000000000000027. Behav Pharmacol. 2014. PMID: 24603340 Free PMC article.
HPLC-MS-MS Determination of ZCZ-011, A Novel Pharmacological Tool for Investigation of the Cannabinoid Receptor in Mouse Brain Using Clean Screen FASt™ Column Extraction.
Poklis JL, Clay DJ, Ignatowska-Jankowska BM, Zanato C, Ross RA, Greig IR, Abdullah RA, Mustafa MA, Lichtman AH, Poklis A. Poklis JL, et al. Among authors: lichtman ah. J Anal Toxicol. 2015 Jun;39(5):353-8. doi: 10.1093/jat/bkv015. Epub 2015 Mar 3. J Anal Toxicol. 2015. PMID: 25737338 Free PMC article.
A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects.
Ignatowska-Jankowska BM, Baillie GL, Kinsey S, Crowe M, Ghosh S, Owens RA, Damaj IM, Poklis J, Wiley JL, Zanda M, Zanato C, Greig IR, Lichtman AH, Ross RA. Ignatowska-Jankowska BM, et al. Among authors: lichtman ah. Neuropsychopharmacology. 2015 Dec;40(13):2948-59. doi: 10.1038/npp.2015.148. Epub 2015 Jun 8. Neuropsychopharmacology. 2015. PMID: 26052038 Free PMC article.
The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.
Wilkerson JL, Niphakis MJ, Grim TW, Mustafa MA, Abdullah RA, Poklis JL, Dewey WL, Akbarali H, Banks ML, Wise LE, Cravatt BF, Lichtman AH. Wilkerson JL, et al. Among authors: lichtman ah. J Pharmacol Exp Ther. 2016 Apr;357(1):145-56. doi: 10.1124/jpet.115.229971. Epub 2016 Jan 20. J Pharmacol Exp Ther. 2016. PMID: 26791602 Free PMC article.
Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice.
Donvito G, Wilkerson JL, Damaj MI, Lichtman AH. Donvito G, et al. Among authors: lichtman ah. J Pharmacol Exp Ther. 2016 Nov;359(2):310-318. doi: 10.1124/jpet.116.236182. Epub 2016 Sep 8. J Pharmacol Exp Ther. 2016. PMID: 27608657 Free PMC article.
The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice.
Wilkerson JL, Ghosh S, Mustafa M, Abdullah RA, Niphakis MJ, Cabrera R, Maldonado RL, Cravatt BF, Lichtman AH. Wilkerson JL, et al. Among authors: lichtman ah. Neuropharmacology. 2017 Mar 1;114:156-167. doi: 10.1016/j.neuropharm.2016.11.015. Epub 2016 Nov 25. Neuropharmacology. 2017. PMID: 27890602 Free PMC article.
359 results