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Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis.
Colón DF, Wanderley CW, Franchin M, Silva CM, Hiroki CH, Castanheira FVS, Donate PB, Lopes AH, Volpon LC, Kavaguti SK, Borges VF, Speck-Hernandez CA, Ramalho F, Carlotti AP, Carmona F, Alves-Filho JC, Liew FY, Cunha FQ. Colón DF, et al. Among authors: castanheira fvs. Crit Care. 2019 Apr 8;23(1):113. doi: 10.1186/s13054-019-2407-8. Crit Care. 2019. PMID: 30961634 Free PMC article.
MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response.
Sônego F, Castanheira FV, Czaikoski PG, Kanashiro A, Souto FO, França RO, Nascimento DC, Freitas A, Spiller F, Cunha LD, Zamboni DS, Alves-Filho JC, Cunha FQ. Sônego F, et al. PLoS One. 2014 Aug 1;9(8):e103734. doi: 10.1371/journal.pone.0103734. eCollection 2014. PLoS One. 2014. PMID: 25084278 Free PMC article.
Legionella longbeachae Is Immunologically Silent and Highly Virulent In Vivo.
Massis LM, Assis-Marques MA, Castanheira FV, Capobianco YJ, Balestra AC, Escoll P, Wood RE, Manin GZ, Correa VM, Alves-Filho JC, Cunha FQ, Buchrieser C, Borges MC, Newton HJ, Zamboni DS. Massis LM, et al. J Infect Dis. 2017 Feb 1;215(3):440-451. doi: 10.1093/infdis/jiw560. J Infect Dis. 2017. PMID: 27932612
Liver X Receptor Activation Impairs Neutrophil Functions and Aggravates Sepsis.
Souto FO, Castanheira FVS, Trevelin SC, Lima BHF, Cebinelli GCM, Turato WM, Auxiliadora-Martins M, Basile-Filho A, Alves-Filho JC, Cunha FQ. Souto FO, et al. Among authors: castanheira fvs. J Infect Dis. 2020 Apr 7;221(9):1542-1553. doi: 10.1093/infdis/jiz635. J Infect Dis. 2020. PMID: 31783409
Paediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunction.
Colón DF, Wanderley CW, Turato WM, Borges VF, Franchin M, Castanheira FVS, Nascimento D, Prado D, Haruo Fernandes de Lima M, Volpon LC, Kavaguti SK, Carlotti AP, Carmona F, Franklin BS, Cunha TM, Alves-Filho JC, Cunha FQ. Colón DF, et al. Among authors: castanheira fvs. Br J Pharmacol. 2024 Apr;181(8):1308-1323. doi: 10.1111/bph.16286. Epub 2024 Jan 11. Br J Pharmacol. 2024. PMID: 37990806
16 results