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Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection.
Damouche A, Lazure T, Avettand-Fènoël V, Huot N, Dejucq-Rainsford N, Satie AP, Mélard A, David L, Gommet C, Ghosn J, Noel N, Pourcher G, Martinez V, Benoist S, Béréziat V, Cosma A, Favier B, Vaslin B, Rouzioux C, Capeau J, Müller-Trutwin M, Dereuddre-Bosquet N, Le Grand R, Lambotte O, Bourgeois C. Damouche A, et al. Among authors: pourcher g. PLoS Pathog. 2015 Sep 24;11(9):e1005153. doi: 10.1371/journal.ppat.1005153. eCollection 2015 Sep. PLoS Pathog. 2015. PMID: 26402858 Free PMC article.
High proportion of PD-1-expressing CD4+ T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence.
Damouche A, Pourcher G, Pourcher V, Benoist S, Busson E, Lataillade JJ, Le Van M, Lazure T, Adam J, Favier B, Vaslin B, Müller-Trutwin M, Lambotte O, Bourgeois C. Damouche A, et al. Among authors: pourcher v, pourcher g. Eur J Immunol. 2017 Dec;47(12):2113-2123. doi: 10.1002/eji.201747060. Epub 2017 Aug 28. Eur J Immunol. 2017. PMID: 28762530 Free article.
The Integrase Inhibitors Dolutegravir and Raltegravir Exert Proadipogenic and Profibrotic Effects and Induce Insulin Resistance in Human/Simian Adipose Tissue and Human Adipocytes.
Gorwood J, Bourgeois C, Pourcher V, Pourcher G, Charlotte F, Mantecon M, Rose C, Morichon R, Atlan M, Le Grand R, Desjardins D, Katlama C, Fève B, Lambotte O, Capeau J, Béréziat V, Lagathu C. Gorwood J, et al. Among authors: pourcher v, pourcher g. Clin Infect Dis. 2020 Dec 17;71(10):e549-e560. doi: 10.1093/cid/ciaa259. Clin Infect Dis. 2020. PMID: 32166319
Comparison of HIV-Infected and Noninfected Patients Undergoing Bariatric Surgery: The ObeVIH Study.
Pourcher V, Capeau J, Dudoit Y, Boccara F, Soulié C, Ndoadoumgue AL, Charlotte F, Fellahi S, Bastard JP, Béréziat V, Lagathu C, Marcelin AG, Peytavin G, Boutron-Ruault MC, Tubbax C, D'Avout D'Auerstaedt A, Valantin MA, Schneider L, Costagliola D, Katlama C, Assoumou L, Pourcher G. Pourcher V, et al. Among authors: pourcher g. J Acquir Immune Defic Syndr. 2022 Jun 1;90(2):240-248. doi: 10.1097/QAI.0000000000002939. J Acquir Immune Defic Syndr. 2022. PMID: 35185138
Detection of SARS-CoV-2 in subcutaneous fat but not visceral fat, and the disruption of fat lymphocyte homeostasis in both fat tissues in the macaque.
Olivo A, Marlin R, Lazure T, Maisonnasse P, Bossevot L, Mouanga C, Lemaitre J, Pourcher G, Benoist S, Le Grand R, Lambotte O, Dereuddre-Bosquet N, Bourgeois C. Olivo A, et al. Among authors: pourcher g. Commun Biol. 2022 Jun 3;5(1):542. doi: 10.1038/s42003-022-03503-9. Commun Biol. 2022. PMID: 35661814 Free PMC article.
61 results