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The oncolytic compound LTX-401 targets the Golgi apparatus.
Zhou H, Sauvat A, Gomes-da-Silva LC, Durand S, Forveille S, Iribarren K, Yamazaki T, Souquere S, Bezu L, Müller K, Leduc M, Liu P, Zhao L, Marabelle A, Zitvogel L, Rekdal Ø, Kepp O, Kroemer G. Zhou H, et al. Cell Death Differ. 2016 Dec;23(12):2031-2041. doi: 10.1038/cdd.2016.86. Epub 2016 Sep 2. Cell Death Differ. 2016. PMID: 27588704 Free PMC article.
eIF2α phosphorylation is pathognomonic for immunogenic cell death.
Bezu L, Sauvat A, Humeau J, Gomes-da-Silva LC, Iribarren K, Forveille S, Garcia P, Zhao L, Liu P, Zitvogel L, Senovilla L, Kepp O, Kroemer G. Bezu L, et al. Cell Death Differ. 2018 Aug;25(8):1375-1393. doi: 10.1038/s41418-017-0044-9. Epub 2018 Jan 22. Cell Death Differ. 2018. PMID: 29358668 Free PMC article.
Recruitment of LC3 to damaged Golgi apparatus.
Gomes-da-Silva LC, Jimenez AJ, Sauvat A, Xie W, Souquere S, Divoux S, Storch M, Sveinbjørnsson B, Rekdal Ø, Arnaut LG, Kepp O, Kroemer G, Perez F. Gomes-da-Silva LC, et al. Cell Death Differ. 2019 Aug;26(8):1467-1484. doi: 10.1038/s41418-018-0221-5. Epub 2018 Oct 22. Cell Death Differ. 2019. PMID: 30349077 Free PMC article.
Oncolysis with DTT-205 and DTT-304 generates immunological memory in cured animals.
Zhou H, Mondragón L, Xie W, Mauseth B, Leduc M, Sauvat A, Gomes-da-Silva LC, Forveille S, Iribarren K, Souquere S, Bezu L, Liu P, Zhao L, Zitvogel L, Sveinbjørnsson B, Eksteen JJ, Rekdal Ø, Kepp O, Kroemer G. Zhou H, et al. Cell Death Dis. 2018 Oct 23;9(11):1086. doi: 10.1038/s41419-018-1127-3. Cell Death Dis. 2018. PMID: 30352991 Free PMC article.
Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus.
Gomes-da-Silva LC, Zhao L, Bezu L, Zhou H, Sauvat A, Liu P, Durand S, Leduc M, Souquere S, Loos F, Mondragón L, Sveinbjørnsson B, Rekdal Ø, Boncompain G, Perez F, Arnaut LG, Kepp O, Kroemer G. Gomes-da-Silva LC, et al. EMBO J. 2018 Jul 2;37(13):e98354. doi: 10.15252/embj.201798354. Epub 2018 May 28. EMBO J. 2018. PMID: 29807932 Free PMC article.
35 results