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Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alteration.
Durante V, de Iure A, Loffredo V, Vaikath N, De Risi M, Paciotti S, Quiroga-Varela A, Chiasserini D, Mellone M, Mazzocchetti P, Calabrese V, Campanelli F, Mechelli A, Di Filippo M, Ghiglieri V, Picconi B, El-Agnaf OM, De Leonibus E, Gardoni F, Tozzi A, Calabresi P. Durante V, et al. Among authors: paciotti s. Brain. 2019 May 1;142(5):1365-1385. doi: 10.1093/brain/awz065. Brain. 2019. PMID: 30927362 Free article.
Cerebrospinal fluid lysosomal enzymes and alpha-synuclein in Parkinson's disease.
Parnetti L, Chiasserini D, Persichetti E, Eusebi P, Varghese S, Qureshi MM, Dardis A, Deganuto M, De Carlo C, Castrioto A, Balducci C, Paciotti S, Tambasco N, Bembi B, Bonanni L, Onofrj M, Rossi A, Beccari T, El-Agnaf O, Calabresi P. Parnetti L, et al. Among authors: paciotti s. Mov Disord. 2014 Jul;29(8):1019-27. doi: 10.1002/mds.25772. Epub 2014 Jan 16. Mov Disord. 2014. PMID: 24436092 Free PMC article.
Lysosomal enzymes in PD: further evidence is needed.
Chiasserini D, Persichetti E, Paciotti S, Beccari T, Parnetti L. Chiasserini D, et al. Among authors: paciotti s. Mov Disord. 2014 Sep;29(10):1329. doi: 10.1002/mds.25976. Epub 2014 Jul 22. Mov Disord. 2014. PMID: 25048840 No abstract available.
Origin of α-mannosidase activity in CSF.
Tasegian A, Paciotti S, Ceccarini MR, Codini M, Moors T, Chiasserini D, Albi E, Winchester B, van de Berg WDJ, Parnetti L, Beccari T. Tasegian A, et al. Among authors: paciotti s. Int J Biochem Cell Biol. 2017 Jun;87:34-37. doi: 10.1016/j.biocel.2017.03.016. Epub 2017 Mar 27. Int J Biochem Cell Biol. 2017. PMID: 28359775
Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson's Disease and Dementia with Lewy Bodies.
Moors TE, Paciotti S, Ingrassia A, Quadri M, Breedveld G, Tasegian A, Chiasserini D, Eusebi P, Duran-Pacheco G, Kremer T, Calabresi P, Bonifati V, Parnetti L, Beccari T, van de Berg WDJ. Moors TE, et al. Among authors: paciotti s. Mol Neurobiol. 2019 Feb;56(2):1344-1355. doi: 10.1007/s12035-018-1090-0. Epub 2018 Jun 8. Mol Neurobiol. 2019. PMID: 29948939 Free PMC article.
42 results