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Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alteration.
Durante V, de Iure A, Loffredo V, Vaikath N, De Risi M, Paciotti S, Quiroga-Varela A, Chiasserini D, Mellone M, Mazzocchetti P, Calabrese V, Campanelli F, Mechelli A, Di Filippo M, Ghiglieri V, Picconi B, El-Agnaf OM, De Leonibus E, Gardoni F, Tozzi A, Calabresi P. Durante V, et al. Among authors: mazzocchetti p. Brain. 2019 May 1;142(5):1365-1385. doi: 10.1093/brain/awz065. Brain. 2019. PMID: 30927362 Free article.
Low doses of Perampanel protect striatal and hippocampal neurons against in vitro ischemia by reversing the ischemia-induced alteration of AMPA receptor subunit composition.
Mazzocchetti P, Mancini A, Sciaccaluga M, Megaro A, Bellingacci L, Di Filippo M, Cesarini EN, Romoli M, Carrano N, Gardoni F, Tozzi A, Calabresi P, Costa C. Mazzocchetti P, et al. Neurobiol Dis. 2020 Jul;140:104848. doi: 10.1016/j.nbd.2020.104848. Epub 2020 Mar 25. Neurobiol Dis. 2020. PMID: 32222474 Free article.
Levodopa-induced plasticity: a double-edged sword in Parkinson's disease?
Calabresi P, Ghiglieri V, Mazzocchetti P, Corbelli I, Picconi B. Calabresi P, et al. Among authors: mazzocchetti p. Philos Trans R Soc Lond B Biol Sci. 2015 Jul 5;370(1672):20140184. doi: 10.1098/rstb.2014.0184. Philos Trans R Soc Lond B Biol Sci. 2015. PMID: 26009763 Free PMC article. Review.
Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system.
Tozzi A, de Iure A, Tantucci M, Durante V, Quiroga-Varela A, Giampà C, Di Mauro M, Mazzocchetti P, Costa C, Di Filippo M, Grassi S, Pettorossi VE, Calabresi P. Tozzi A, et al. Among authors: mazzocchetti p. Front Cell Neurosci. 2015 May 27;9:192. doi: 10.3389/fncel.2015.00192. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26074768 Free PMC article.
Striatal spreading depolarization: Possible implication in levodopa-induced dyskinetic-like behavior.
de Iure A, Napolitano F, Beck G, Quiroga Varela A, Durante V, Sciaccaluga M, Mazzocchetti P, Megaro A, Tantucci M, Cardinale A, Punzo D, Mancini A, Costa C, Ghiglieri V, Tozzi A, Picconi B, Papa SM, Usiello A, Calabresi P. de Iure A, et al. Among authors: mazzocchetti p. Mov Disord. 2019 Jun;34(6):832-844. doi: 10.1002/mds.27632. Epub 2019 Feb 13. Mov Disord. 2019. PMID: 30759320 Free PMC article.
Effects of safinamide on the glutamatergic striatal network in experimental Parkinson's disease.
Sciaccaluga M, Mazzocchetti P, Bastioli G, Ghiglieri V, Cardinale A, Mosci P, Caccia C, Keywood C, Melloni E, Padoani G, Vailati S, Picconi B, Calabresi P, Tozzi A. Sciaccaluga M, et al. Among authors: mazzocchetti p. Neuropharmacology. 2020 Jun 15;170:108024. doi: 10.1016/j.neuropharm.2020.108024. Epub 2020 Mar 3. Neuropharmacology. 2020. PMID: 32142791
Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis.
Mancini A, Tantucci M, Mazzocchetti P, de Iure A, Durante V, Macchioni L, Giampà C, Alvino A, Gaetani L, Costa C, Tozzi A, Calabresi P, Di Filippo M. Mancini A, et al. Among authors: mazzocchetti p. Neurobiol Dis. 2018 May;113:97-108. doi: 10.1016/j.nbd.2018.01.002. Epub 2018 Jan 9. Neurobiol Dis. 2018. PMID: 29325869
17 results