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The discovery and development of gefapixant.
Ford AP, Dillon MP, Kitt MM, Gever JR. Ford AP, et al. Auton Neurosci. 2021 Nov;235:102859. doi: 10.1016/j.autneu.2021.102859. Epub 2021 Jul 31. Auton Neurosci. 2021. PMID: 34403981
AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist.
Gever JR, Soto R, Henningsen RA, Martin RS, Hackos DH, Panicker S, Rubas W, Oglesby IB, Dillon MP, Milla ME, Burnstock G, Ford AP. Gever JR, et al. Among authors: ford ap. Br J Pharmacol. 2010 Jul;160(6):1387-98. doi: 10.1111/j.1476-5381.2010.00796.x. Br J Pharmacol. 2010. PMID: 20590629 Free PMC article.
P2X3 receptor antagonism reduces the occurrence of apnoeas in newborn rats.
Katayama PL, Abdala AP, Charles I, Pijacka W, Salgado HC, Gever J, Ford AP, Paton JFR. Katayama PL, et al. Among authors: ford ap. Respir Physiol Neurobiol. 2020 Jun;277:103438. doi: 10.1016/j.resp.2020.103438. Epub 2020 Apr 5. Respir Physiol Neurobiol. 2020. PMID: 32259688 Free PMC article.
Pharmacology of P2X channels.
Gever JR, Cockayne DA, Dillon MP, Burnstock G, Ford AP. Gever JR, et al. Among authors: ford ap. Pflugers Arch. 2006 Aug;452(5):513-37. doi: 10.1007/s00424-006-0070-9. Epub 2006 Apr 29. Pflugers Arch. 2006. PMID: 16649055 Review.
113 results