Nguyen L - Search Results

1

1H-Pyrrolo[3,2-b]pyridine GluN2B-Selective Negative Allosteric Modulators.

Chrovian CC, Soyode-Johnson A, Wall JL, Rech JC, Schoellerman J, Lord B, Coe KJ, Carruthers NI, Nguyen L, Jiang X, Koudriakova T, Balana B, Letavic MA. Chrovian CC, et al. Among authors: nguyen l. ACS Med Chem Lett. 2019 Jan 10;10(3):261-266. doi: 10.1021/acsmedchemlett.8b00542. eCollection 2019 Mar 14. ACS Med Chem Lett. 2019. PMID: 30891123 Free PMC article.

2

Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-b]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders.

Chrovian CC, Soyode-Johnson A, Stenne B, Pippel DJ, Schoellerman J, Lord B, Needham AS, Xia C, Coe KJ, Sepassi K, Schoetens F, Scott B, Nguyen L, Jiang X, Koudriakova T, Balana B, Letavic MA. Chrovian CC, et al. Among authors: nguyen l. J Med Chem. 2020 Sep 10;63(17):9181-9196. doi: 10.1021/acs.jmedchem.9b02113. Epub 2020 Aug 28. J Med Chem. 2020. PMID: 32787105

3

Novel Phenyl-Substituted 5,6-Dihydro-[1,2,4]triazolo[4,3-a]pyrazine P2X7 Antagonists with Robust Target Engagement in Rat Brain.

Chrovian CC, Soyode-Johnson A, Ao H, Bacani GM, Carruthers NI, Lord B, Nguyen L, Rech JC, Wang Q, Bhattacharya A, Letavic MA. Chrovian CC, et al. Among authors: nguyen l. ACS Chem Neurosci. 2016 Apr 20;7(4):490-7. doi: 10.1021/acschemneuro.5b00303. Epub 2016 Jan 15. ACS Chem Neurosci. 2016. PMID: 26752113

4

Comparison of the ex vivo receptor occupancy profile of ketamine to several NMDA receptor antagonists in mouse hippocampus.

Lord B, Wintmolders C, Langlois X, Nguyen L, Lovenberg T, Bonaventure P. Lord B, et al. Among authors: nguyen l. Eur J Pharmacol. 2013 Sep 5;715(1-3):21-5. doi: 10.1016/j.ejphar.2013.06.028. Epub 2013 Jul 16. Eur J Pharmacol. 2013. PMID: 23872376

5

Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.

Wyatt RM, Fraser I, Welty N, Lord B, Wennerholm M, Sutton S, Ameriks MK, Dugovic C, Yun S, White A, Nguyen L, Koudriakova T, Tian G, Suarez J, Szewczuk L, Bonnette W, Ahn K, Ghosh B, Flores CM, Connolly PJ, Zhu B, Macielag MJ, Brandt MR, Chevalier K, Zhang SP, Lovenberg T, Bonaventure P. Wyatt RM, et al. Among authors: nguyen l. J Pharmacol Exp Ther. 2020 Mar;372(3):339-353. doi: 10.1124/jpet.119.262139. Epub 2019 Dec 9. J Pharmacol Exp Ther. 2020. PMID: 31818916

6

LC/MS/MS Profiling of Tissue Oxysterols and its Application in Dextran Sodium Sulphate Induced Mouse Colitis Models.

Wu J, McDuffie JE, Song J, Harris MC, Raymond H, Chen Y, Nguyen L, Nguyen S, Kanerva J, McAllister HM, Deng X, Mani N, Liu C, Sun S. Wu J, et al. Among authors: nguyen l, nguyen s. Curr Top Med Chem. 2017;17(24):2781-2790. doi: 10.2174/1568026617666170713165519. Curr Top Med Chem. 2017. PMID: 28714418

7

Retraction notice to "A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells".

Mehta PP, Kung PP, Yamazaki S, Walls M, Shen A, Nguyen L, Gehring MR, Los G, Smeal T, Yin MJ. Mehta PP, et al. Among authors: nguyen l. Cancer Lett. 2018 May 28;422:132. doi: 10.1016/j.canlet.2018.03.019. Cancer Lett. 2018. PMID: 29579439 No abstract available.

8

RETRACTED: A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells.

Mehta PP, Kung PP, Yamazaki S, Walls M, Shen A, Nguyen L, Gehring MR, Los G, Smeal T, Yin MJ. Mehta PP, et al. Among authors: nguyen l. Cancer Lett. 2011 Jan 1;300(1):30-9. doi: 10.1016/j.canlet.2010.09.002. Cancer Lett. 2011. PMID: 20926183 Retracted.

9

Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available heat shock protein 90 inhibitor in a human tumor xenograft mouse model.

Yamazaki S, Nguyen L, Vekich S, Shen Z, Yin MJ, Mehta PP, Kung PP, Vicini P. Yamazaki S, et al. Among authors: nguyen l. J Pharmacol Exp Ther. 2011 Sep;338(3):964-73. doi: 10.1124/jpet.111.181339. Epub 2011 Jun 16. J Pharmacol Exp Ther. 2011. PMID: 21680888

10

Quantitative analysis of PD 0332991 in xenograft mouse tumor tissue by a 96-well supported liquid extraction format and liquid chromatography/mass spectrometry.

Nguyen L, Zhong WZ, Painter CL, Zhang C, Rahavendran SV, Shen Z. Nguyen L, et al. J Pharm Biomed Anal. 2010 Nov 2;53(3):228-34. doi: 10.1016/j.jpba.2010.02.031. Epub 2010 Feb 26. J Pharm Biomed Anal. 2010. PMID: 20236782

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