Chipuk JE - Search Results

1

MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network.

Elkholi R, Abraham-Enachescu I, Trotta AP, Rubio-Patiño C, Mohammed JN, Luna-Vargas MPA, Gelles JD, Kaminetsky JR, Serasinghe MN, Zou C, Ali S, McStay GP, Pfleger CM, Chipuk JE. Elkholi R, et al. Among authors: chipuk je. Mol Cell. 2019 May 2;74(3):452-465.e7. doi: 10.1016/j.molcel.2019.02.012. Epub 2019 Mar 14. Mol Cell. 2019. PMID: 30879903 Free PMC article.

2

Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis.

Spierings D, McStay G, Saleh M, Bender C, Chipuk J, Maurer U, Green DR. Spierings D, et al. Science. 2005 Oct 7;310(5745):66-7. doi: 10.1126/science.1117105. Science. 2005. PMID: 16210526

3

The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment.

Elkholi R, Floros KV, Chipuk JE. Elkholi R, et al. Among authors: chipuk je. Genes Cancer. 2011 May;2(5):523-37. doi: 10.1177/1947601911417177. Genes Cancer. 2011. PMID: 21901166 Free PMC article.

4

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis.

Chipuk JE, McStay GP, Bharti A, Kuwana T, Clarke CJ, Siskind LJ, Obeid LM, Green DR. Chipuk JE, et al. Cell. 2012 Mar 2;148(5):988-1000. doi: 10.1016/j.cell.2012.01.038. Cell. 2012. PMID: 22385963 Free PMC article.

5

Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens.

Anvekar RA, Asciolla JJ, Lopez-Rivera E, Floros KV, Izadmehr S, Elkholi R, Belbin G, Sikora AG, Chipuk JE. Anvekar RA, et al. Among authors: chipuk je. Cell Death Dis. 2012 Nov 15;3(11):e420. doi: 10.1038/cddis.2012.161. Cell Death Dis. 2012. PMID: 23152056 Free PMC article.

6

How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis.

Elkholi R, Chipuk JE. Elkholi R, et al. Among authors: chipuk je. Bioessays. 2014 Jan;36(1):46-51. doi: 10.1002/bies.201300117. Epub 2013 Oct 24. Bioessays. 2014. PMID: 24323920 Free PMC article. Review.

7

Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models.

Zhang X, Lv H, Zhou Q, Elkholi R, Chipuk JE, Reddy MV, Reddy EP, Gallo JM. Zhang X, et al. Among authors: chipuk je. Mol Cancer Ther. 2014 May;13(5):1105-16. doi: 10.1158/1535-7163.MCT-13-0847. Epub 2014 Feb 25. Mol Cancer Ther. 2014. PMID: 24568969 Free PMC article.

8

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance.

Serasinghe MN, Missert DJ, Asciolla JJ, Podgrabinska S, Wieder SY, Izadmehr S, Belbin G, Skobe M, Chipuk JE. Serasinghe MN, et al. Among authors: chipuk je. Oncogene. 2015 Feb 12;34(7):857-67. doi: 10.1038/onc.2014.21. Epub 2014 Mar 10. Oncogene. 2015. PMID: 24608435 Free PMC article.

9

Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination.

Chong RA, Wu K, Spratt DE, Yang Y, Lee C, Nayak J, Xu M, Elkholi R, Tappin I, Li J, Hurwitz J, Brown BD, Chipuk JE, Chen ZJ, Sanchez R, Shaw GS, Huang L, Pan ZQ. Chong RA, et al. Among authors: chipuk je. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8434-9. doi: 10.1073/pnas.1407849111. Epub 2014 May 27. Proc Natl Acad Sci U S A. 2014. PMID: 24912152 Free PMC article.

10

B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.

Renault TT, Elkholi R, Bharti A, Chipuk JE. Renault TT, et al. Among authors: chipuk je. J Biol Chem. 2014 Sep 19;289(38):26481-26491. doi: 10.1074/jbc.M114.569632. Epub 2014 Aug 5. J Biol Chem. 2014. PMID: 25096574 Free PMC article.

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