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Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders.
Hjelm BE, Rollins B, Morgan L, Sequeira A, Mamdani F, Pereira F, Damas J, Webb MG, Weber MD, Schatzberg AF, Barchas JD, Lee FS, Akil H, Watson SJ, Myers RM, Chao EC, Kimonis V, Thompson PM, Bunney WE, Vawter MP. Hjelm BE, et al. Among authors: morgan l. Nucleic Acids Res. 2019 Jun 4;47(10):e59. doi: 10.1093/nar/gkz164. Nucleic Acids Res. 2019. PMID: 30869147 Free PMC article.
Analysis of whole genome biomarker expression in blood and brain.
Rollins B, Martin MV, Morgan L, Vawter MP. Rollins B, et al. Among authors: morgan l. Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):919-36. doi: 10.1002/ajmg.b.31062. Am J Med Genet B Neuropsychiatr Genet. 2010. PMID: 20127885 Free PMC article.
Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide.
Sequeira A, Morgan L, Walsh DM, Cartagena PM, Choudary P, Li J, Schatzberg AF, Watson SJ, Akil H, Myers RM, Jones EG, Bunney WE, Vawter MP. Sequeira A, et al. Among authors: morgan l. PLoS One. 2012;7(4):e35367. doi: 10.1371/journal.pone.0035367. Epub 2012 Apr 30. PLoS One. 2012. PMID: 22558144 Free PMC article.
Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder.
Das SC, Hjelm BE, Rollins BL, Sequeira A, Morgan L, Omidsalar AA, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. Das SC, et al. Among authors: morgan l. Transl Psychiatry. 2022 Aug 30;12(1):353. doi: 10.1038/s41398-022-02127-1. Transl Psychiatry. 2022. PMID: 36042222 Free PMC article.
Large Common Mitochondrial DNA Deletions Are Associated with a Mitochondrial SNP T14798C Near the 3' Breakpoints.
Hjelm BE, Ramiro C, Rollins BL, Omidsalar AA, Gerke DS, Das SC, Sequeira A, Morgan L, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. Hjelm BE, et al. Among authors: morgan l. Complex Psychiatry. 2023 Jan;8(3-4):90-98. doi: 10.1159/000528051. Epub 2022 Nov 14. Complex Psychiatry. 2023. PMID: 36778651 Free PMC article.
1,445 results