Fas receptor induces apoptosis of synovial bone and cartilage progenitor populations and promotes bone loss in antigen-induced arthritis.
Lazić Mosler E, Lukač N, Flegar D, Fadljević M, Radanović I, Cvija H, Kelava T, Ivčević S, Šućur A, Markotić A, Katavić V, Marušić A, Grčević D, Kovačić N.
Lazić Mosler E, et al. Among authors: markotic a.
FASEB J. 2019 Mar;33(3):3330-3342. doi: 10.1096/fj.201801426R. Epub 2018 Nov 1.
FASEB J. 2019.
PMID: 30383451
Results showed that Fas(-/-) mice developed attenuated arthritis characterized by preserved epiphyseal bone and cartilage. A proportion of the earliest CD200(+) bone and cartilage progenitors was reduced in WT mice with arthritis and was unaltered in Fas(-/-) mice. ...-Laz …
Results showed that Fas(-/-) mice developed attenuated arthritis characterized by preserved epiphyseal bone and cartilage. A proporti …