Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins.
Mazzone A, Gibbons SJ, Eisenman ST, Strege PR, Zheng T, D'Amato M, Ordog T, Fernandez-Zapico ME, Farrugia G.
Mazzone A, et al.
FASEB J. 2019 May;33(5):6632-6642. doi: 10.1096/fj.201802373R. Epub 2019 Feb 25.
FASEB J. 2019.
PMID: 30802137
Free PMC article.
We conclude that Gli1 and Gli2 repress ANO1 by a novel mechanism that is independent of Gli cleavage and that has a role in gastrointestinal function.-Mazzone, A., Gibbons, S. J., Eisenman, S. T., Strege, P. R., Zheng, T., D'Amato, M., Ordog, T., Ferna …
We conclude that Gli1 and Gli2 repress ANO1 by a novel mechanism that is independent of Gli cleavage and that has a role in ga …