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Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.
Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Matsui H, Yoshikawa T. Takagi T, et al. Among authors: ichikawa h. J Pharmacol Exp Ther. 2009 Oct;331(1):255-64. doi: 10.1124/jpet.109.152702. Epub 2009 Jul 23. J Pharmacol Exp Ther. 2009. PMID: 19628634
Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency.
Harusato A, Naito Y, Takagi T, Uchiyama K, Mizushima K, Hirai Y, Yamada S, Tuji T, Yoriki H, Horie R, Inoue K, Fukumoto K, Handa O, Ishikawa T, Kokura S, Minamiyama Y, Ichikawa H, Muto A, Igarashi K, Yoshikawa T. Harusato A, et al. Among authors: ichikawa h. Free Radic Res. 2011 Jun;45(6):717-27. doi: 10.3109/10715762.2011.574287. Epub 2011 Apr 8. Free Radic Res. 2011. PMID: 21473739
1,897 results