Jia G - Search Results

1

Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates.

Zhang X, Wei LH, Wang Y, Xiao Y, Liu J, Zhang W, Yan N, Amu G, Tang X, Zhang L, Jia G. Zhang X, et al. Among authors: jia g. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2919-2924. doi: 10.1073/pnas.1820574116. Epub 2019 Feb 4. Proc Natl Acad Sci U S A. 2019. PMID: 30718435 Free PMC article.

2

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.

Jia G, Yang CG, Yang S, Jian X, Yi C, Zhou Z, He C. Jia G, et al. FEBS Lett. 2008 Oct 15;582(23-24):3313-9. doi: 10.1016/j.febslet.2008.08.019. Epub 2008 Sep 5. FEBS Lett. 2008. PMID: 18775698 Free PMC article.

3

Duplex interrogation by a direct DNA repair protein in search of base damage.

Yi C, Chen B, Qi B, Zhang W, Jia G, Zhang L, Li CJ, Dinner AR, Yang CG, He C. Yi C, et al. Among authors: jia g. Nat Struct Mol Biol. 2012 Jun 3;19(7):671-6. doi: 10.1038/nsmb.2320. Nat Struct Mol Biol. 2012. PMID: 22659876 Free PMC article.

4

Development of cell-active N6-methyladenosine RNA demethylase FTO inhibitor.

Chen B, Ye F, Yu L, Jia G, Huang X, Zhang X, Peng S, Chen K, Wang M, Gong S, Zhang R, Yin J, Li H, Yang Y, Liu H, Zhang J, Zhang H, Zhang A, Jiang H, Luo C, Yang CG. Chen B, et al. Among authors: jia g. J Am Chem Soc. 2012 Oct 31;134(43):17963-71. doi: 10.1021/ja3064149. Epub 2012 Oct 17. J Am Chem Soc. 2012. PMID: 23045983

5

A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation.

Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, Dai Q, Chen W, He C. Liu J, et al. Among authors: jia g. Nat Chem Biol. 2014 Feb;10(2):93-5. doi: 10.1038/nchembio.1432. Epub 2013 Dec 6. Nat Chem Biol. 2014. PMID: 24316715 Free PMC article.

6

Methylation modifications in eukaryotic messenger RNA.

Liu J, Jia G. Liu J, et al. Among authors: jia g. J Genet Genomics. 2014 Jan 20;41(1):21-33. doi: 10.1016/j.jgg.2013.10.002. Epub 2013 Nov 9. J Genet Genomics. 2014. PMID: 24480744 Review.

7

Decreased N(6)-methyladenosine in peripheral blood RNA from diabetic patients is associated with FTO expression rather than ALKBH5.

Shen F, Huang W, Huang JT, Xiong J, Yang Y, Wu K, Jia GF, Chen J, Feng YQ, Yuan BF, Liu SM. Shen F, et al. J Clin Endocrinol Metab. 2015 Jan;100(1):E148-54. doi: 10.1210/jc.2014-1893. J Clin Endocrinol Metab. 2015. PMID: 25303482 Free PMC article.

8

FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.

Zhao X, Yang Y, Sun BF, Shi Y, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, Wang X, Huang CM, Fu Y, Ge XM, Song SH, Jeong HS, Yanagisawa H, Niu Y, Jia GF, Wu W, Tong WM, Okamoto A, He C, Rendtlew Danielsen JM, Wang XJ, Yang YG. Zhao X, et al. Cell Res. 2014 Dec;24(12):1403-19. doi: 10.1038/cr.2014.151. Epub 2014 Nov 21. Cell Res. 2014. PMID: 25412662 Free PMC article.

9

Unique features of the m6A methylome in Arabidopsis thaliana.

Luo GZ, MacQueen A, Zheng G, Duan H, Dore LC, Lu Z, Liu J, Chen K, Jia G, Bergelson J, He C. Luo GZ, et al. Among authors: jia g. Nat Commun. 2014 Nov 28;5:5630. doi: 10.1038/ncomms6630. Nat Commun. 2014. PMID: 25430002 Free PMC article.

10

Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.

Huang Y, Yan J, Li Q, Li J, Gong S, Zhou H, Gan J, Jiang H, Jia GF, Luo C, Yang CG. Huang Y, et al. Nucleic Acids Res. 2015 Jan;43(1):373-84. doi: 10.1093/nar/gku1276. Epub 2014 Dec 1. Nucleic Acids Res. 2015. PMID: 25452335 Free PMC article.

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