Caplen NJ - Search Results

1

MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival.

Lee CS, Lee LC, Yuan TL, Chakka S, Fellmann C, Lowe SW, Caplen NJ, McCormick F, Luo J. Lee CS, et al. Among authors: caplen nj. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4508-4517. doi: 10.1073/pnas.1817494116. Epub 2019 Feb 1. Proc Natl Acad Sci U S A. 2019. PMID: 30709910 Free PMC article.

2

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.

Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, Wolfsberg TG, Umayam L, Lee JC, Hughes CM, Shanmugam KS, Bhattacharjee A, Meyerson M, Collins FS. Scacheri PC, et al. Among authors: caplen nj. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1892-7. doi: 10.1073/pnas.0308698100. Epub 2004 Feb 9. Proc Natl Acad Sci U S A. 2004. PMID: 14769924 Free PMC article.

3

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening.

Garimella SV, Gehlhaus K, Dine JL, Pitt JJ, Grandin M, Chakka S, Nau MM, Caplen NJ, Lipkowitz S. Garimella SV, et al. Among authors: caplen nj. Breast Cancer Res. 2014 Apr 17;16(2):R41. doi: 10.1186/bcr3645. Breast Cancer Res. 2014. PMID: 24745479 Free PMC article.

4

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.

Ou O, Huppi K, Chakka S, Gehlhaus K, Dubois W, Patel J, Chen J, Mackiewicz M, Jones TL, Pitt JJ, Martin SE, Goldsmith P, Simmons JK, Mock BA, Caplen NJ. Ou O, et al. Among authors: caplen nj. Cancer Lett. 2014 Nov 28;354(2):336-47. doi: 10.1016/j.canlet.2014.08.043. Epub 2014 Sep 1. Cancer Lett. 2014. PMID: 25193464 Free PMC article.

5

Selective targeting of KRAS-mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-mutant cells.

Hara T, Jones MF, Subramanian M, Li XL, Ou O, Zhu Y, Yang Y, Wakefield LM, Hussain SP, Gaedcke J, Ried T, Luo J, Caplen NJ, Lal A. Hara T, et al. Among authors: caplen nj. Oncotarget. 2014 Sep 15;5(17):7635-50. doi: 10.18632/oncotarget.2284. Oncotarget. 2014. PMID: 25245095 Free PMC article.

6

Identification of therapeutic targets applicable to clinical strategies in ovarian cancer.

Kim MK, Caplen N, Chakka S, Hernandez L, House C, Pongas G, Jordan E, Annunziata CM. Kim MK, et al. BMC Cancer. 2016 Aug 24;16(1):678. doi: 10.1186/s12885-016-2675-5. BMC Cancer. 2016. PMID: 27558154 Free PMC article.

7

BRD4 facilitates DNA damage response and represses CBX5/Heterochromatin protein 1 (HP1).

Pongas G, Kim MK, Min DJ, House CD, Jordan E, Caplen N, Chakka S, Ohiri J, Kruhlak MJ, Annunziata CM. Pongas G, et al. Oncotarget. 2017 May 3;8(31):51402-51415. doi: 10.18632/oncotarget.17572. eCollection 2017 Aug 1. Oncotarget. 2017. PMID: 28881656 Free PMC article.

8

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems.

Caplen NJ, Parrish S, Imani F, Fire A, Morgan RA. Caplen NJ, et al. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9742-7. doi: 10.1073/pnas.171251798. Epub 2001 Jul 31. Proc Natl Acad Sci U S A. 2001. PMID: 11481446 Free PMC article.

9

Fusion transcripts: Unexploited vulnerabilities in cancer?

Neckles C, Sundara Rajan S, Caplen NJ. Neckles C, et al. Among authors: caplen nj. Wiley Interdiscip Rev RNA. 2020 Jan;11(1):e1562. doi: 10.1002/wrna.1562. Epub 2019 Aug 13. Wiley Interdiscip Rev RNA. 2020. PMID: 31407506 Free PMC article. Review.

10

RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors.

Martin SE, Wu ZH, Gehlhaus K, Jones TL, Zhang YW, Guha R, Miyamoto S, Pommier Y, Caplen NJ. Martin SE, et al. Among authors: caplen nj. Curr Cancer Drug Targets. 2011 Oct;11(8):976-86. doi: 10.2174/156800911797264734. Curr Cancer Drug Targets. 2011. PMID: 21834757 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

86 results

Search Page