Chen CT - Search Results

1

Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A.

Tian JN, Wu RH, Chen SL, Chen CT, Yueh A. Tian JN, et al. Among authors: chen ct, chen sl. J Gen Virol. 2019 Mar;100(3):457-470. doi: 10.1099/jgv.0.001227. Epub 2019 Feb 1. J Gen Virol. 2019. PMID: 30707666

2

Structure-based drug design of a novel family of PPARgamma partial agonists: virtual screening, X-ray crystallography, and in vitro/in vivo biological activities.

Lu IL, Huang CF, Peng YH, Lin YT, Hsieh HP, Chen CT, Lien TW, Lee HJ, Mahindroo N, Prakash E, Yueh A, Chen HY, Goparaju CM, Chen X, Liao CC, Chao YS, Hsu JT, Wu SY. Lu IL, et al. Among authors: chen ct, chen hy, chen x. J Med Chem. 2006 May 4;49(9):2703-12. doi: 10.1021/jm051129s. J Med Chem. 2006. PMID: 16640330

3

A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus.

Yeh TK, Kang IJ, Hsu TA, Lee YC, Lee CC, Hsu SJ, Tian YW, Yang HY, Chen CT, Chao YS, Yueh A, Chern JH. Yeh TK, et al. Among authors: chen ct. Eur J Med Chem. 2019 Apr 1;167:245-268. doi: 10.1016/j.ejmech.2019.02.016. Epub 2019 Feb 6. Eur J Med Chem. 2019. PMID: 30772607

4

A Dengue Virus Type 2 (DENV-2) NS4B-Interacting Host Factor, SERP1, Reduces DENV-2 Production by Suppressing Viral RNA Replication.

Tian JN, Yang CC, Chuang CK, Tsai MH, Wu RH, Chen CT, Yueh A. Tian JN, et al. Among authors: chen ct. Viruses. 2019 Aug 27;11(9):787. doi: 10.3390/v11090787. Viruses. 2019. PMID: 31461934 Free PMC article.

5

A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses.

Yang CC, Hu HS, Lin HM, Wu PS, Wu RH, Tian JN, Wu SH, Tsou LK, Song JS, Chen HW, Chern JH, Chen CT, Yueh A. Yang CC, et al. Among authors: chen ct, chen hw. Antiviral Res. 2019 Dec;172:104636. doi: 10.1016/j.antiviral.2019.104636. Epub 2019 Oct 23. Antiviral Res. 2019. PMID: 31654671

6

Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodies.

Shen KY, Yang CH, Chen CT, Ho HM, Chiu FF, Huang CY, Liao HC, Hsu CW, Yu GY, Liao CL, Chen HW, Huang MH, Liu SJ. Shen KY, et al. Among authors: chen ct, chen hw. J Med Virol. 2023 Jan;95(1):e28370. doi: 10.1002/jmv.28370. J Med Virol. 2023. PMID: 36458553 Free PMC article.

7

Discovery of M Protease Inhibitors Encoded by SARS-CoV-2.

Hung HC, Ke YY, Huang SY, Huang PN, Kung YA, Chang TY, Yen KJ, Peng TT, Chang SE, Huang CT, Tsai YR, Wu SH, Lee SJ, Lin JH, Liu BS, Sung WC, Shih SR, Chen CT, Hsu JT. Hung HC, et al. Among authors: chen ct. Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00872-20. doi: 10.1128/AAC.00872-20. Print 2020 Aug 20. Antimicrob Agents Chemother. 2020. PMID: 32669265 Free PMC article.

8

Development of Stem-Cell-Mobilizing Agents Targeting CXCR4 Receptor for Peripheral Blood Stem Cell Transplantation and Beyond.

Wu CH, Song JS, Kuan HH, Wu SH, Chou MC, Jan JJ, Tsou LK, Ke YY, Chen CT, Yeh KC, Wang SY, Yeh TK, Tseng CT, Huang CL, Wu MH, Kuo PC, Lee CJ, Shia KS. Wu CH, et al. Among authors: chen ct. J Med Chem. 2018 Feb 8;61(3):818-833. doi: 10.1021/acs.jmedchem.7b01322. Epub 2018 Jan 27. J Med Chem. 2018. PMID: 29314840

9

Inhibition of SARS-CoV-2 by Highly Potent Broad-Spectrum Anti-Coronaviral Tylophorine-Based Derivatives.

Yang CW, Lee YZ, Hsu HY, Jan JT, Lin YL, Chang SY, Peng TT, Yang RB, Liang JJ, Liao CC, Chao TL, Pang YH, Kao HC, Huang WZ, Lin JH, Chang CP, Niu GH, Wu SH, Sytwu HK, Chen CT, Lee SJ. Yang CW, et al. Among authors: chen ct. Front Pharmacol. 2020 Dec 14;11:606097. doi: 10.3389/fphar.2020.606097. eCollection 2020. Front Pharmacol. 2020. PMID: 33519469 Free PMC article.

10

Repurposing old drugs as antiviral agents for coronaviruses.

Yang CW, Peng TT, Hsu HY, Lee YZ, Wu SH, Lin WH, Ke YY, Hsu TA, Yeh TK, Huang WZ, Lin JH, Sytwu HK, Chen CT, Lee SJ. Yang CW, et al. Among authors: chen ct. Biomed J. 2020 Aug;43(4):368-374. doi: 10.1016/j.bj.2020.05.003. Epub 2020 May 23. Biomed J. 2020. PMID: 32563698 Free PMC article.

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