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Eupatoriopicrin Inhibits Pro-inflammatory Functions of Neutrophils via Suppression of IL-8 and TNF-alpha Production and p38 and ERK 1/2 MAP Kinases.
Michalak B, Piwowarski JP, Granica S, Waltenberger B, Atanasov AG, Khan SY, Breuss JM, Uhrin P, Żyżyńska-Granica B, Stojakowska A, Stuppner H, Kiss AK. Michalak B, et al. Among authors: stuppner h. J Nat Prod. 2019 Feb 22;82(2):375-385. doi: 10.1021/acs.jnatprod.8b00939. Epub 2019 Jan 17. J Nat Prod. 2019. PMID: 30653318
Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma.
Fakhrudin N, Ladurner A, Atanasov AG, Heiss EH, Baumgartner L, Markt P, Schuster D, Ellmerer EP, Wolber G, Rollinger JM, Stuppner H, Dirsch VM. Fakhrudin N, et al. Among authors: stuppner h. Mol Pharmacol. 2010 Apr;77(4):559-66. doi: 10.1124/mol.109.062141. Epub 2010 Jan 11. Mol Pharmacol. 2010. PMID: 20064974 Free PMC article.
Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine.
Waltenberger B, Schuster D, Paramapojn S, Gritsanapan W, Wolber G, Rollinger JM, Stuppner H. Waltenberger B, et al. Among authors: stuppner h. Phytomedicine. 2011 Jan 15;18(2-3):119-33. doi: 10.1016/j.phymed.2010.08.002. Epub 2010 Sep 20. Phytomedicine. 2011. PMID: 20851587 Free PMC article.
Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques.
Noha SM, Atanasov AG, Schuster D, Markt P, Fakhrudin N, Heiss EH, Schrammel O, Rollinger JM, Stuppner H, Dirsch VM, Wolber G. Noha SM, et al. Among authors: stuppner h. Bioorg Med Chem Lett. 2011 Jan 1;21(1):577-83. doi: 10.1016/j.bmcl.2010.10.051. Epub 2010 Oct 20. Bioorg Med Chem Lett. 2011. PMID: 21078555 Free PMC article.
Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro.
Baumgartner L, Sosa S, Atanasov AG, Bodensieck A, Fakhrudin N, Bauer J, Favero GD, Ponti C, Heiss EH, Schwaiger S, Ladurner A, Widowitz U, Loggia RD, Rollinger JM, Werz O, Bauer R, Dirsch VM, Tubaro A, Stuppner H. Baumgartner L, et al. Among authors: stuppner h. J Nat Prod. 2011 Aug 26;74(8):1779-86. doi: 10.1021/np200343t. Epub 2011 Jul 29. J Nat Prod. 2011. PMID: 21800856 Free PMC article.
289 results