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The impact of the rs8005161 polymorphism on G protein-coupled receptor GPR65 (TDAG8) pH-associated activation in intestinal inflammation.
BMC Gastroenterol. 2019 Jan 7;19(1):2. doi: 10.1186/s12876-018-0922-8.
BMC Gastroenterol. 2019.
PMID: 30616622
Free PMC article.
G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation.
de Vallière C, Wang Y, Eloranta JJ, Vidal S, Clay I, Spalinger MR, Tcymbarevich I, Terhalle A, Ludwig MG, Suply T, Fried M, Kullak-Ublick GA, Frey-Wagner I, Scharl M, Seuwen K, Wagner CA, Rogler G.
de Vallière C, et al.
Inflamm Bowel Dis. 2015 Jun;21(6):1269-81. doi: 10.1097/MIB.0000000000000375.
Inflamm Bowel Dis. 2015.
PMID: 25856770
Free PMC article.
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Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).
de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA.
de Vallière C, et al.
Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810. doi: 10.1016/j.jcmgh.2016.06.003. eCollection 2016 Nov.
Cell Mol Gastroenterol Hepatol. 2016.
PMID: 28174749
Free PMC article.
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Lack of the pH-sensing Receptor TDAG8 [GPR65] in Macrophages Plays a Detrimental Role in Murine Models of Inflammatory Bowel Disease.
Tcymbarevich I, Richards SM, Russo G, Kühn-Georgijevic J, Cosin-Roger J, Baebler K, Lang S, Bengs S, Atrott K, Bettoni C, Gruber S, Frey-Wagner I, Scharl M, Misselwitz B, Wagner CA, Seuwen K, Rogler G, Ruiz PA, Spalinger M, de Vallière C.
Tcymbarevich I, et al.
J Crohns Colitis. 2019 Feb 1;13(2):245-258. doi: 10.1093/ecco-jcc/jjy152.
J Crohns Colitis. 2019.
PMID: 30535144
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The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment.
de Vallière C, Vidal S, Clay I, Jurisic G, Tcymbarevich I, Lang S, Ludwig MG, Okoniewski M, Eloranta JJ, Kullak-Ublick GA, Wagner CA, Rogler G, Seuwen K.
de Vallière C, et al.
Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G475-90. doi: 10.1152/ajpgi.00408.2014. Epub 2015 Jul 23.
Am J Physiol Gastrointest Liver Physiol. 2015.
PMID: 26206859
Free article.
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The ESRP1-GPR137 axis contributes to intestinal pathogenesis.
Mager LF, Koelzer VH, Stuber R, Thoo L, Keller I, Koeck I, Langenegger M, Simillion C, Pfister SP, Faderl M, Genitsch V, Tcymbarevich I, Juillerat P, Li X, Xia Y, Karamitopoulou E, Lyck R, Zlobec I, Hapfelmeier S, Bruggmann R, McCoy KD, Macpherson AJ, Müller C, Beutler B, Krebs P.
Mager LF, et al.
Elife. 2017 Oct 4;6:e28366. doi: 10.7554/eLife.28366.
Elife. 2017.
PMID: 28975893
Free PMC article.
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