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Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer.
Laverty D, Desai R, Uchański T, Masiulis S, Stec WJ, Malinauskas T, Zivanov J, Pardon E, Steyaert J, Miller KW, Aricescu AR. Laverty D, et al. Among authors: aricescu ar. Nature. 2019 Jan;565(7740):516-520. doi: 10.1038/s41586-018-0833-4. Epub 2019 Jan 2. Nature. 2019. PMID: 30602789 Free PMC article.
Crystal structure of a human GABAA receptor.
Miller PS, Aricescu AR. Miller PS, et al. Among authors: aricescu ar. Nature. 2014 Aug 21;512(7514):270-5. doi: 10.1038/nature13293. Epub 2014 Jun 8. Nature. 2014. PMID: 24909990 Free PMC article.
Structural basis for GABAA receptor potentiation by neurosteroids.
Miller PS, Scott S, Masiulis S, De Colibus L, Pardon E, Steyaert J, Aricescu AR. Miller PS, et al. Among authors: aricescu ar. Nat Struct Mol Biol. 2017 Nov;24(11):986-992. doi: 10.1038/nsmb.3484. Epub 2017 Oct 9. Nat Struct Mol Biol. 2017. PMID: 28991263 Free PMC article.
GABAA receptor signalling mechanisms revealed by structural pharmacology.
Masiulis S, Desai R, Uchański T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR. Masiulis S, et al. Among authors: aricescu ar. Nature. 2019 Jan;565(7740):454-459. doi: 10.1038/s41586-018-0832-5. Epub 2019 Jan 2. Nature. 2019. PMID: 30602790 Free PMC article.
A structural perspective on GABAA receptor pharmacology.
Scott S, Aricescu AR. Scott S, et al. Among authors: aricescu ar. Curr Opin Struct Biol. 2019 Feb;54:189-197. doi: 10.1016/j.sbi.2019.03.023. Epub 2019 May 23. Curr Opin Struct Biol. 2019. PMID: 31129381 Review.
Single-particle cryo-EM at atomic resolution.
Nakane T, Kotecha A, Sente A, McMullan G, Masiulis S, Brown PMGE, Grigoras IT, Malinauskaite L, Malinauskas T, Miehling J, Uchański T, Yu L, Karia D, Pechnikova EV, de Jong E, Keizer J, Bischoff M, McCormack J, Tiemeijer P, Hardwick SW, Chirgadze DY, Murshudov G, Aricescu AR, Scheres SHW. Nakane T, et al. Among authors: aricescu ar. Nature. 2020 Nov;587(7832):152-156. doi: 10.1038/s41586-020-2829-0. Epub 2020 Oct 21. Nature. 2020. PMID: 33087931 Free PMC article.
Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Uchański T, Masiulis S, Fischer B, Kalichuk V, López-Sánchez U, Zarkadas E, Weckener M, Sente A, Ward P, Wohlkönig A, Zögg T, Remaut H, Naismith JH, Nury H, Vranken W, Aricescu AR, Pardon E, Steyaert J. Uchański T, et al. Among authors: aricescu ar. Nat Methods. 2021 Jan;18(1):60-68. doi: 10.1038/s41592-020-01001-6. Epub 2021 Jan 6. Nat Methods. 2021. PMID: 33408403 Free PMC article.
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