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Fluorophore Labeling Affects the Cellular Accumulation and Gene Silencing Activity of Cholesterol-Modified siRNAs In Vitro.
Nucleic Acid Ther. 2019 Feb;29(1):33-43. doi: 10.1089/nat.2018.0745. Epub 2018 Dec 18.
Nucleic Acid Ther. 2019.
PMID: 30562146
Trimeric Small Interfering RNAs and Their Cholesterol-Containing Conjugates Exhibit Improved Accumulation in Tumors, but Dramatically Reduced Silencing Activity.
Chernikov IV, Gladkikh DV, Karelina UA, Meschaninova MI, Ven'yaminova AG, Vlassov VV, Chernolovskaya EL.
Chernikov IV, et al. Among authors: karelina ua.
Molecules. 2020 Apr 18;25(8):1877. doi: 10.3390/molecules25081877.
Molecules. 2020.
PMID: 32325757
Free PMC article.
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