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NmeCas9 is an intrinsically high-fidelity genome-editing platform.
Amrani N, Gao XD, Liu P, Edraki A, Mir A, Ibraheim R, Gupta A, Sasaki KE, Wu T, Donohoue PD, Settle AH, Lied AM, McGovern K, Fuller CK, Cameron P, Fazzio TG, Zhu LJ, Wolfe SA, Sontheimer EJ. Amrani N, et al. Among authors: cameron p. Genome Biol. 2018 Dec 5;19(1):214. doi: 10.1186/s13059-018-1591-1. Genome Biol. 2018. PMID: 30518407 Free PMC article.
Mapping the genomic landscape of CRISPR-Cas9 cleavage.
Cameron P, Fuller CK, Donohoue PD, Jones BN, Thompson MS, Carter MM, Gradia S, Vidal B, Garner E, Slorach EM, Lau E, Banh LM, Lied AM, Edwards LS, Settle AH, Capurso D, Llaca V, Deschamps S, Cigan M, Young JK, May AP. Cameron P, et al. Nat Methods. 2017 Jun;14(6):600-606. doi: 10.1038/nmeth.4284. Epub 2017 May 1. Nat Methods. 2017. PMID: 28459459
Harnessing type I CRISPR-Cas systems for genome engineering in human cells.
Cameron P, Coons MM, Klompe SE, Lied AM, Smith SC, Vidal B, Donohoue PD, Rotstein T, Kohrs BW, Nyer DB, Kennedy R, Banh LM, Williams C, Toh MS, Irby MJ, Edwards LS, Lin CH, Owen ALG, Künne T, van der Oost J, Brouns SJJ, Slorach EM, Fuller CK, Gradia S, Kanner SB, May AP, Sternberg SH. Cameron P, et al. Nat Biotechnol. 2019 Dec;37(12):1471-1477. doi: 10.1038/s41587-019-0310-0. Epub 2019 Nov 18. Nat Biotechnol. 2019. PMID: 31740839
Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells.
Donohoue PD, Pacesa M, Lau E, Vidal B, Irby MJ, Nyer DB, Rotstein T, Banh L, Toh MS, Gibson J, Kohrs B, Baek K, Owen ALG, Slorach EM, van Overbeek M, Fuller CK, May AP, Jinek M, Cameron P. Donohoue PD, et al. Among authors: cameron p. Mol Cell. 2021 Sep 2;81(17):3637-3649.e5. doi: 10.1016/j.molcel.2021.07.035. Mol Cell. 2021. PMID: 34478654 Free article.
Structural basis for Cas9 off-target activity.
Pacesa M, Lin CH, Cléry A, Saha A, Arantes PR, Bargsten K, Irby MJ, Allain FH, Palermo G, Cameron P, Donohoue PD, Jinek M. Pacesa M, et al. Among authors: cameron p. Cell. 2022 Oct 27;185(22):4067-4081.e21. doi: 10.1016/j.cell.2022.09.026. Cell. 2022. PMID: 36306733 Free PMC article.
Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas.
Burger BT, Beaton BP, Campbell MA, Brett BT, Rohrer MS, Plummer S, Barnes D, Jiang K, Naswa S, Lange J, Ott A, Alger E, Rincon G, Rounsley S, Betthauser J, Mtango NR, Benne JA, Hammerand J, Durfee CJ, Rotolo ML, Cameron P, Lied AM, Irby MJ, Nyer DB, Fuller CK, Gradia S, Kanner SB, Park KE, Waters J, Simpson S, Telugu BP, Salgado BC, Brandariz-Nuñez A, Rowland RRR, Culbertson M, Rice E, Cigan AM. Burger BT, et al. Among authors: cameron p. CRISPR J. 2024 Feb;7(1):12-28. doi: 10.1089/crispr.2023.0061. CRISPR J. 2024. PMID: 38353617
Clinical and Imaging Characteristics, Care Pathways, and Outcomes of Traumatic Epidural Hematomas: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study.
Pisică D, Volovici V, Yue JK, van Essen TA, den Boogert HF, Vande Vyvere T, Haitsma I, Nieboer D, Markowitz AJ, Yuh EL, Steyerberg EW, Peul WC, Dirven CMF, Menon DK, Manley GT, Maas AIR, Lingsma HF; CENTER-TBI Participants and Investigators. Pisică D, et al. Neurosurgery. 2024 May 21. doi: 10.1227/neu.0000000000002982. Online ahead of print. Neurosurgery. 2024. PMID: 38771081
Correction: Identifying areas of Australia with high out-of-hospital cardiac arrest incidence and low bystander cardiopulmonary resuscitation rates: A retrospective, observational study.
Doan T, Howell S, Ball S, Finn J, Cameron P, Bosley E, Dicker B, Faddy S, Nehme Z, Heriot N, Swain A, Thorrowgood M, Thomas A, Perillo S, McDermott M, Smith T, Smith K, Belcher J, Bray J; Aus-ROC OHCA Epistry Management Committee. Doan T, et al. Among authors: cameron p. PLoS One. 2024 May 9;19(5):e0303681. doi: 10.1371/journal.pone.0303681. eCollection 2024. PLoS One. 2024. PMID: 38722859 Free PMC article.
1,289 results