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Small benzothiazole molecule induces apoptosis and prevents metastasis through DNA interaction and c-MYC gene supression in diffuse-type gastric adenocarcinoma cell line.
Mesquita FP, Pinto LC, Soares BM, de Sousa Portilho AJ, da Silva EL, de Farias Ramos IN, Khayat AS, Moreira-Nunes CA, Bezerra MM, de Lucas Chazin E, Vasconcelos TRA, Burbano RMR, de Moraes MEA, Montenegro RC. Mesquita FP, et al. Among authors: da silva el. Chem Biol Interact. 2018 Oct 1;294:118-127. doi: 10.1016/j.cbi.2018.08.006. Epub 2018 Aug 11. Chem Biol Interact. 2018. PMID: 30107152
Telomerase (hTERT) Overexpression Reveals a Promising Prognostic Biomarker and Therapeutical Target in Different Clinical Subtypes of Pediatric Acute Lymphoblastic Leukaemia.
Nogueira BMD, da Costa Pantoja L, da Silva EL, Mello Júnior FAR, Teixeira EB, Wanderley AV, da Silva Maués JH, de Moraes Filho MO, de Moraes MEA, Montenegro RC, Khayat AS, Moreira-Nunes CA. Nogueira BMD, et al. Among authors: da silva maues jh, da costa pantoja l, da silva el. Genes (Basel). 2021 Oct 17;12(10):1632. doi: 10.3390/genes12101632. Genes (Basel). 2021. PMID: 34681025 Free PMC article.
Kinase Inhibition in Relapsed/Refractory Leukemia and Lymphoma Settings: Recent Prospects into Clinical Investigations.
Machado CB, de Pinho Pessoa FMC, da Silva EL, da Costa Pantoja L, Ribeiro RM, de Moraes Filho MO, de Moraes MEA, Montenegro RC, Burbano RMR, Khayat AS, Moreira-Nunes CA. Machado CB, et al. Among authors: da costa pantoja l, da silva el. Pharmaceutics. 2021 Oct 2;13(10):1604. doi: 10.3390/pharmaceutics13101604. Pharmaceutics. 2021. PMID: 34683897 Free PMC article. Review.
Solid Tumors and Kinase Inhibition: Management and Therapy Efficacy Evolution.
de Pinho Pessoa FMC, Machado CB, da Silva EL, da Costa Pantoja L, Ribeiro RM, de Moraes MEA, de Moraes Filho MO, Montenegro RC, Khayat AS, Moreira-Nunes CA. de Pinho Pessoa FMC, et al. Among authors: da costa pantoja l, da silva el. Int J Mol Sci. 2022 Mar 30;23(7):3830. doi: 10.3390/ijms23073830. Int J Mol Sci. 2022. PMID: 35409190 Free PMC article. Review.
1,4-Naphthoquinone (CNN1) Induces Apoptosis through DNA Damage and Promotes Upregulation of H2AFX in Leukemia Multidrug Resistant Cell Line.
de Sousa Portilho AJ, da Silva EL, Bezerra ECA, Moraes Rego Gomes CBS, Ferreira V, de Moraes MEA, da Rocha DR, Burbano RMR, Moreira-Nunes CA, Montenegro RC. de Sousa Portilho AJ, et al. Among authors: da rocha dr, da silva el. Int J Mol Sci. 2022 Jul 23;23(15):8105. doi: 10.3390/ijms23158105. Int J Mol Sci. 2022. PMID: 35897681 Free PMC article.
Anticancer potential of mebendazole against chronic myeloid leukemia: in silico and in vitro studies revealed new insights about the mechanism of action.
Daniel JP, Mesquita FP, Da Silva EL, de Souza PFN, Lima LB, de Oliveira LLB, de Moraes MEA, Moreira-Nunes CFA, Burbano RMR, Zanatta G, Montenegro RC. Daniel JP, et al. Among authors: da silva el. Front Pharmacol. 2022 Aug 25;13:952250. doi: 10.3389/fphar.2022.952250. eCollection 2022. Front Pharmacol. 2022. PMID: 36091760 Free PMC article.
Antitumoral effect of novel synthetic 8-hydroxy-2-((4-nitrophenyl)thio)naphthalene-1,4-dione (CNN16) via ROS-mediated DNA damage, apoptosis and anti-migratory effect in colon cancer cell line.
da Silva EL, Mesquita FP, Ramos INF, Gomes CBSMR, Moreira CDS, Ferreira VF, da Rocha DR, Bahia MO, Moreira-Nunes CA, de Souza CRT, Burbano RMR, Montenegro RC. da Silva EL, et al. Among authors: da rocha dr. Toxicol Appl Pharmacol. 2022 Dec 1;456:116256. doi: 10.1016/j.taap.2022.116256. Epub 2022 Oct 5. Toxicol Appl Pharmacol. 2022. PMID: 36208702
124 results