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121 results

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Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation.
Nonomura K, Lukacs V, Sweet DT, Goddard LM, Kanie A, Whitwam T, Ranade SS, Fujimori T, Kahn ML, Patapoutian A. Nonomura K, et al. Among authors: patapoutian a. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12817-12822. doi: 10.1073/pnas.1817070115. Epub 2018 Nov 27. Proc Natl Acad Sci U S A. 2018. PMID: 30482854 Free PMC article.
Large-scale analysis of the human and mouse transcriptomes.
Su AI, Cooke MP, Ching KA, Hakak Y, Walker JR, Wiltshire T, Orth AP, Vega RG, Sapinoso LM, Moqrich A, Patapoutian A, Hampton GM, Schultz PG, Hogenesch JB. Su AI, et al. Among authors: patapoutian a. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4465-70. doi: 10.1073/pnas.012025199. Epub 2002 Mar 19. Proc Natl Acad Sci U S A. 2002. PMID: 11904358 Free PMC article.
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype.
Blasius AL, Dubin AE, Petrus MJ, Lim BK, Narezkina A, Criado JR, Wills DN, Xia Y, Moresco EM, Ehlers C, Knowlton KU, Patapoutian A, Beutler B. Blasius AL, et al. Among authors: patapoutian a. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19413-8. doi: 10.1073/pnas.1117020108. Epub 2011 Nov 15. Proc Natl Acad Sci U S A. 2011. PMID: 22087007 Free PMC article.
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis.
Coste B, Houge G, Murray MF, Stitziel N, Bandell M, Giovanni MA, Philippakis A, Hoischen A, Riemer G, Steen U, Steen VM, Mathur J, Cox J, Lebo M, Rehm H, Weiss ST, Wood JN, Maas RL, Sunyaev SR, Patapoutian A. Coste B, et al. Among authors: patapoutian a. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4667-72. doi: 10.1073/pnas.1221400110. Epub 2013 Mar 4. Proc Natl Acad Sci U S A. 2013. PMID: 23487782 Free PMC article.
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors.
Maksimovic S, Nakatani M, Baba Y, Nelson AM, Marshall KL, Wellnitz SA, Firozi P, Woo SH, Ranade S, Patapoutian A, Lumpkin EA. Maksimovic S, et al. Among authors: patapoutian a. Nature. 2014 May 29;509(7502):617-21. doi: 10.1038/nature13250. Epub 2014 Apr 6. Nature. 2014. PMID: 24717432 Free PMC article.
Piezo2 is required for Merkel-cell mechanotransduction.
Woo SH, Ranade S, Weyer AD, Dubin AE, Baba Y, Qiu Z, Petrus M, Miyamoto T, Reddy K, Lumpkin EA, Stucky CL, Patapoutian A. Woo SH, et al. Among authors: patapoutian a. Nature. 2014 May 29;509(7502):622-6. doi: 10.1038/nature13251. Epub 2014 Apr 6. Nature. 2014. PMID: 24717433 Free PMC article.
Piezo1, a mechanically activated ion channel, is required for vascular development in mice.
Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A. Ranade SS, et al. Among authors: patapoutian a. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52. doi: 10.1073/pnas.1409233111. Epub 2014 Jun 23. Proc Natl Acad Sci U S A. 2014. PMID: 24958852 Free PMC article.
Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, Lewin GR, Patapoutian A. Ranade SS, et al. Among authors: patapoutian a. Nature. 2014 Dec 4;516(7529):121-5. doi: 10.1038/nature13980. Nature. 2014. PMID: 25471886 Free PMC article.
Piezo1 links mechanical forces to red blood cell volume.
Cahalan SM, Lukacs V, Ranade SS, Chien S, Bandell M, Patapoutian A. Cahalan SM, et al. Among authors: patapoutian a. Elife. 2015 May 22;4:e07370. doi: 10.7554/eLife.07370. Elife. 2015. PMID: 26001274 Free PMC article.
121 results