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The SLC16A11 risk haplotype is associated with decreased insulin action, higher transaminases and large-size adipocytes.
Almeda-Valdes P, Gómez Velasco DV, Arellano Campos O, Bello-Chavolla OY, Del Rocío Sevilla-González M, Viveros Ruiz T, Martagón Rosado AJ, Bautista CJ, Muñoz Hernandez L, Cruz-Bautista I, Moreno-Macias H, Huerta-Chagoya A, Rodríguez-Álvarez KG, Walford GA, Jacobs SBR, Guillen Pineda LE, Ordoñez-Sánchez ML, Roldan-Valadez E, Azpiroz J, Furuzawa-Carballeda J, Clark P, Herrera-Hernández MF, Zambrano E, Florez JC, Tusié Luna MT, Aguilar-Salinas CA. Almeda-Valdes P, et al. Eur J Endocrinol. 2019 Feb 1;180(2):99-107. doi: 10.1530/EJE-18-0677. Eur J Endocrinol. 2019. PMID: 30475225
Early-onset type 2 diabetes: metabolic and genetic characterization in the mexican population.
Aguilar-Salinas CA, Reyes-Rodríguez E, Ordóñez-Sánchez ML, Torres MA, Ramírez-Jiménez S, Domínguez-López A, Martínez-Francois JR, Velasco-Pérez ML, Alpizar M, García-García E, Gómez-Pérez F, Rull J, Tusié-Luna MT. Aguilar-Salinas CA, et al. J Clin Endocrinol Metab. 2001 Jan;86(1):220-6. doi: 10.1210/jcem.86.1.7134. J Clin Endocrinol Metab. 2001. PMID: 11232004
Locus on chromosome 6p linked to elevated HDL cholesterol serum levels and to protection against premature atherosclerosis in a kindred with familial hypercholesterolemia.
Canizales-Quinteros S, Aguilar-Salinas CA, Reyes-Rodríguez E, Riba L, Rodríguez-Torres M, Ramírez-Jiménez S, Huertas-Vázquez A, Fragoso-Ontiveros V, Zentella-Dehesa A, Ventura-Gallegos JL, Vega-Hernández G, López-Estrada A, Aurón-Gómez M, Gómez-Pérez F, Rull J, Cox NJ, Bell GI, Tusié-Luna MT. Canizales-Quinteros S, et al. Circ Res. 2003 Mar 21;92(5):569-76. doi: 10.1161/01.RES.0000064174.69165.66. Epub 2003 Feb 27. Circ Res. 2003. PMID: 12609970
Mutations in MODY genes are not common cause of early-onset type 2 diabetes in Mexican families.
Domínguez-López A, Miliar-García A, Segura-Kato YX, Riba L, Esparza-López R, Ramírez-Jiménez S, Rodríguez-Torres M, Canizales-Quinteros S, Cabrera-Vásquez S, Fragoso-Ontiveros V, Aguilar-Salinas CA, Altamirano-Bustamante N, Calzada-León R, Robles-Valdés C, Bravo-Ríos LE, Tusié-Luna MT. Domínguez-López A, et al. JOP. 2005 May 10;6(3):238-45. JOP. 2005. PMID: 15883474
HNF-1alpha G574S is a functional variant with decreased transactivation activity.
Navalón-García K, Mendoza-Alcantar L, Díaz-Vargas ME, Martínez-Godínez MA, Reyna-Garfias H, Aguilar-Salinas CA, Riba L, Canizales-Quinteros S, Villarreal-Molina T, González-Chávez A, Argueta-Villamar V, Tusié-Luna MT, Miliar-García A. Navalón-García K, et al. Diabet Med. 2006 Dec;23(12):1295-300. doi: 10.1111/j.1464-5491.2006.02008.x. Diabet Med. 2006. PMID: 17116178
439 results