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Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors.
Hyrsova L, Vanduchova A, Dusek J, Smutny T, Carazo A, Maresova V, Trejtnar F, Barta P, Anzenbacher P, Dvorak Z, Pavek P. Hyrsova L, et al. Among authors: anzenbacher p. Toxicol Lett. 2019 Jan;300:81-91. doi: 10.1016/j.toxlet.2018.10.028. Epub 2018 Oct 27. Toxicol Lett. 2019. PMID: 30394306
Disposition of sanguinarine in the rat.
Vecera R, Klejdus B, Kosina P, Orolin J, Stiborová M, Smrcek S, Vicar J, Dvorák Z, Ulrichová J, Kubán V, Anzenbacher P, Simánek V. Vecera R, et al. Among authors: anzenbacher p. Xenobiotica. 2007 May;37(5):549-58. doi: 10.1080/00498250701230542. Xenobiotica. 2007. PMID: 17523056
Silybin is metabolized by cytochrome P450 2C8 in vitro.
Jancová P, Anzenbacherová E, Papousková B, Lemr K, Luzná P, Veinlichová A, Anzenbacher P, Simánek V. Jancová P, et al. Among authors: anzenbacher p. Drug Metab Dispos. 2007 Nov;35(11):2035-9. doi: 10.1124/dmd.107.016410. Epub 2007 Aug 1. Drug Metab Dispos. 2007. PMID: 17670841
236 results